Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13054629 | 1.00 | USP2 (0.68) | USP2ALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL1965555 | 1.00 | USP2 (0.68) | USP2ALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL27881284 | 1.00 | USP2 (0.68) | USP2ALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL9329637 | 0.91 | ALDH1A1 (0.55) | USP2ALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL10849155 | 0.91 | ALDH1A1 (0.55) | USP2ALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL28454145 | 0.91 | ALDH1A1 (0.55) | USP2ALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL10007317 | 0.91 | ALDH1A1 (0.55) | USP2ALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL10847415 | 0.91 | ALDH1A1 (0.55) | USP2ALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL11506586 | 0.91 | ALDH1A1 (0.55) | USP2ALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL4948952 | 0.91 | USP2 (0.70) | USP2ALDH1A1CYP3A4MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10932484-B2 | Inhibitory activity of acetogenins against Listeria monocytogenes | INSTITUTO TECNOLOGICO Y DE ESTUDIOS SUPERIORES DE MONTERREY (MX) | 2021-03-02 | — | — | US | disclosed |
| US-20180103671-A1 | INHIBITORY ACTIVITY OF ACETOGENINS AGAINST LISTERIA MONOCYTOGENES | INSTITUTO TECNOLOGICO Y DE ESTUDIOS SUPERIORES DE MONTERREY (MX) | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180103671-A1 | INHIBITORY ACTIVITY OF ACETOGENINS AGAINST LISTERIA MONOCYTOGENES | LTN1, LCT, LSS | USP2 1358/4885ALDH1A1 505/4885CYP3A4 4070/4885 |
| US-10932484-B2 | Inhibitory activity of acetogenins against Listeria monocytogenes | LTN1, LCT, LSS | USP2 1358/4885ALDH1A1 505/4885CYP3A4 4070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.