SCHEMBL2007305

SCHEMBL2007305

F[Ti](Oc1cccc(-c2ccccc2)c1)=C(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 2/20 0.42
KMO O15229 1/20 0.41
FFAR1 O14842 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40
PRSS1 P07477 1/20 0.40
PRSS2 P07478 1/20 0.40
PRSS3 P35030 1/20 0.40
MAPT P10636 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
NR4A2 P43354 1/20 0.39
BCL2L1 Q07817 1/20 0.39
MCL1 Q07820 1/20 0.39
RXRA P19793 2/20 0.39
RXRB P28702 2/20 0.39
AKR1C3 P42330 1/20 0.39
HDAC8 Q9BY41 1/20 0.38
ALOX5 P09917 1/20 0.38
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL720978 0.98 MRGPRX4 (0.41) MRGPRX4KMOFFAR1FFAR4PRSS1
Hydrochloric Acid SCHEMBL720163 0.80 FFAR1 (0.40) FFAR1FFAR4MAPTTDP1RXRA
Hydrochloric Acid SCHEMBL724813 0.77 ACHE (0.41) FFAR1MAPTTDP1NR4A2RXRA
Hydrochloric Acid SCHEMBL3803758 0.76 RXRA (0.41) MRGPRX4FFAR1FFAR4MAPTTDP1
SCHEMBL2008075 0.75 LTA4H (0.41) MRGPRX4FFAR1FFAR4
Hydrochloric Acid SCHEMBL724570 0.75 SMN1; SMN2 (0.34) MAPT
Hydrochloric Acid SCHEMBL721078 0.74 LTA4H (0.41) MRGPRX4FFAR1FFAR4
SCHEMBL27890434 0.71 CYP1A1 (0.42) FFAR1FFAR4RXRARXRB
SCHEMBL4536542 0.69 LTA4H (0.60) FFAR1FFAR4MAPTAKR1C3MEN1
SCHEMBL30731588 0.68 LTA4H (0.57) FFAR1FFAR4MAPTAKR1C3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011074688-A1 PRODUCTION PROCESS OF OLEFIN POLYMERIZATION CATALYST AND OLEFIN POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-23 WO disclosed