Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25509748 | 0.87 | HTT (0.41) | HTTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL16794437 | 0.83 | MEN1 (0.40) | HTTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL14913985 | 0.81 | HTT (0.39) | HTTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL14917639 | 0.81 | LMNA (0.47) | HTTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL16622729 | 0.81 | HTT (0.38) | HTTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL31497522 | 0.81 | HTT (0.38) | HTTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL173687 | 0.81 | HTT (0.38) | HTTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL14912696 | 0.80 | MITF (0.51) | HTTALDH1A1MEN1KMT2ACYP2C19 | |
| SCHEMBL611566 | 0.79 | HTT (0.38) | HTTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL25888930 | 0.78 | MEN1 (0.37) | HTTALDH1A1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071794-A1 | TYK2 INHIBITORS AND USES THEREOF | NIMBUS LAKSHMI, INC. (US) | 2018-04-19 | — | — | WO | disclosed |