Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24609048 | 0.98 | MEN1 (0.49) | POLBMEN1KMT2AMAPK1CHRM1 | |
| SCHEMBL24609120 | 0.90 | MAPK1 (0.46) | POLBMEN1KMT2AMAPK1CHRM1 | |
| SCHEMBL24609204 | 0.90 | SMN1; SMN2 (0.52) | POLBMEN1KMT2AMAPK1CHRM1 | |
| SCHEMBL24609202 | 0.89 | CHRM2 (0.54) | MEN1KMT2AMAPK1CHRM1ALDH1A1 | |
| SCHEMBL23799245 | 0.86 | POLB (0.48) | POLBMEN1KMT2AMAPK1CHRM1 | |
| SCHEMBL20066038 | 0.84 | HSD11B1 (0.48) | POLBMEN1KMT2AMAPK1CHRM1 | |
| SCHEMBL24609142 | 0.84 | GAA (0.48) | POLBMEN1KMT2AMAPK1CHRM1 | |
| SCHEMBL20066008 | 0.82 | CYP2D6 (0.48) | POLBMEN1KMT2AMAPK1CHRM1 | |
| SCHEMBL24609124 | 0.81 | NOS2 (0.51) | POLBMEN1KMT2AMAPK1CHRM1 | |
| SCHEMBL20066073 | 0.80 | CYP2D6 (0.49) | POLBMEN1KMT2AMAPK1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069732-A1 | HETEROCYCLIC COMPOUNDS HAVING ACTIVITY AS MODULATORS OF MUSCARINIC M1 AND/OR M4 RECEPTORS IN THE TREATMENT OF CNS DISEASES AND PAINS. | HEPTARES THERAPEUTICS LIMITED (GB) | 2018-04-19 | — | — | WO | disclosed |