Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 10/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.31 |
| ▸ | GUSB | P08236 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Camphor SCHEMBL1151878 | 0.68 | ALDH1A1 (1.00) | KMT2AMEN1LMNAALDH1A1MAPT | |
| Camphor SCHEMBL15542393 | 0.68 | ALDH1A1 (1.00) | KMT2AMEN1LMNAALDH1A1MAPT | |
| Camphor SCHEMBL2037672 | 0.68 | ALDH1A1 (1.00) | KMT2AMEN1LMNAALDH1A1MAPT | |
| Camphor SCHEMBL285280 | 0.68 | ALDH1A1 (1.00) | KMT2AMEN1LMNAALDH1A1MAPT | |
| Camphor SCHEMBL13248606 | 0.68 | ALDH1A1 (1.00) | KMT2AMEN1LMNAALDH1A1MAPT | |
| Camphor SCHEMBL16068 | 0.68 | ALDH1A1 (1.00) | KMT2AMEN1LMNAALDH1A1MAPT | |
| Camphor SCHEMBL16582770 | 0.68 | ALDH1A1 (1.00) | KMT2AMEN1LMNAALDH1A1MAPT | |
| (-)-Camphor SCHEMBL1701376 | 0.68 | ALDH1A1 (1.00) | KMT2AMEN1LMNAALDH1A1MAPT | |
| Camphor SCHEMBL1712401 | 0.68 | ALDH1A1 (1.00) | KMT2AMEN1LMNAALDH1A1MAPT | |
| Camphor SCHEMBL29673264 | 0.68 | ALDH1A1 (1.00) | KMT2AMEN1LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10208048-B2 | RSV antiviral pyrazolo- and triazolo-pyrimidine compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2019-02-19 | — | — | US | disclosed |
| US-20180105529-A1 | RSV ANTIVIRAL PYRAZOLO- AND TRIAZOLO-PYRIMIDINE COMPOUNDS | JANSSEN SCIENCES IRELAND UC (IE) | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10208048-B2 | RSV antiviral pyrazolo- and triazolo-pyrimidine compounds | ZC3HAV1, MAVS, TYMP | KMT2A 4144/4885MEN1 4788/4885LMNA 3900/4885 |
| US-20180105529-A1 | RSV ANTIVIRAL PYRAZOLO- AND TRIAZOLO-PYRIMIDINE COMPOUNDS | ZC3HAV1, MAVS, TYMP | KMT2A 4144/4885MEN1 4788/4885LMNA 3900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.