SCHEMBL20074370

SCHEMBL20074370

CCC/C=C/C(Cl)=C\C=C(/C)CCCC

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.35
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
PPARG P37231 2/20 0.30
PPARA Q07869 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27686509 0.76 CES1 (0.43) ALDH1A1TP53PPARGPPARA
SCHEMBL21882660 0.76 ALDH1A1 (0.37) ALDH1A1TP53
SCHEMBL23718834 0.70 TSHR (0.38) PTPN1ALDH1A1TP53PPARGPPARA
SCHEMBL15546326 0.69 FASN (0.44) PTPN1TP53PPARGPPARA
SCHEMBL21277524 0.69 TSHR (0.43) PTPN1ALDH1A1TP53PPARGPPARA
SCHEMBL24649713 0.68 ALDH1A1 (0.37) ALDH1A1TP53
SCHEMBL23716369 0.68 TSHR (0.44) PTPN1ALDH1A1PPARGPPARA
SCHEMBL22551392 0.66 CES1 (0.36) ALDH1A1TP53
SCHEMBL22551391 0.66 CES1 (0.36) ALDH1A1TP53
SCHEMBL17504427 0.66 PPARG (0.36) PTPN1ALDH1A1TP53PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018069769-A1 PHARMACEUTICAL COMPOSITION FOR INHIBITING NEOINTIMA FORMATION OF BLOOD VESSEL DAIICHI SANKYO COMPANY, LIMITED (JP) 2018-04-19 WO disclosed