Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23718834 | 0.94 | TSHR (0.38) | ALDH1A1TP53CES1TSHRCES2 | |
| SCHEMBL24092186 | 0.88 | TSHR (0.32) | TSHR | |
| SCHEMBL27686509 | 0.80 | CES1 (0.43) | ALDH1A1TP53CES1TSHRCES2 | |
| SCHEMBL8583365 | 0.76 | — | — | |
| SCHEMBL184574 | 0.76 | — | — | |
| SCHEMBL184575 | 0.76 | — | — | |
| SCHEMBL20837673 | 0.76 | CES1 (0.31) | ALDH1A1CES1TSHRHPGDCES2 | |
| SCHEMBL20074370 | 0.76 | PTPN1 (0.35) | ALDH1A1TP53 | |
| SCHEMBL18998415 | 0.73 | TSHR (0.35) | ALDH1A1CES1TSHRCES2 | |
| SCHEMBL13359172 | 0.73 | CES1 (0.42) | ALDH1A1TP53CES1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200102287-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2020-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200102287-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | ALDH1A1 840/4885TP53 4876/4885CES1 318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.