Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399537 | 0.82 | CA1 (0.43) | NQO2CA1CA2NAMPTMALT1 | |
| SCHEMBL30754099 | 0.82 | APLNR (0.36) | NQO2CA1CA2GAA | |
| SCHEMBL5109167 | 0.81 | CA1 (0.43) | NQO2CA1CA2TDP1NAMPT | |
| SCHEMBL5109992 | 0.80 | CA2 (0.45) | NQO2CA1CA2TDP1NAMPT | |
| SCHEMBL19300685 | 0.79 | TACR1 (0.44) | NQO2CA1CA2TDP1NAMPT | |
| SCHEMBL3696922 | 0.78 | NQO2 (0.47) | NQO2CA1CA2TDP1NAMPT | |
| SCHEMBL8401477 | 0.77 | CTSS (0.50) | NQO2NAMPTIDO1MEN1KMT2A | |
| SCHEMBL23684682 | 0.75 | CACNA1H (0.42) | NQO2CA1CA2DRD2MEN1 | |
| SCHEMBL19026304 | 0.75 | CA1 (0.41) | NQO2CA1CA2TDP1NAMPT | |
| SCHEMBL8399561 | 0.75 | IDO1 (0.55) | CA1CA2NAMPTMALT1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071606-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR | Arvinas, Inc. (US) | 2018-04-19 | — | — | WO | disclosed |