SCHEMBL20076512

SCHEMBL20076512

C=C(Nc1ccc(Cl)c(-c2ccc(F)c(N)c2F)c1)C1C(c2cc(C)c(C)c(Br)c2)C1(C)Cl

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.33
SLC9A1 P19634 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21020815 0.91 SLC9A1 (0.33) PIM1SLC9A1
SCHEMBL20076590 0.81 SLC9A1 (0.34) SLC9A1
SCHEMBL21020809 0.81 MEN1 (0.31)
SCHEMBL21022007 0.76 MEN1 (0.30)
SCHEMBL21020543 0.74 NPC1 (0.33) SLC9A1
SCHEMBL21022270 0.71 SLC9A1 (0.38) SLC9A1
SCHEMBL20076582 0.71 SLC9A1 (0.43) SLC9A1
SCHEMBL20076609 0.71 KMT2A (0.35)
SCHEMBL20076794 0.71 CYP2C9 (0.30)
SCHEMBL21020810 0.71 LMNA (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018071327-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-04-19 WO disclosed