SCHEMBL21022007

SCHEMBL21022007

C=C(Nc1ccc(Cl)c(-c2ccc(N)cc2C)c1)C1C(c2ccc(C)c(F)c2)C1(C)Cl

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21022270 0.87 SLC9A1 (0.38)
SCHEMBL21020815 0.81 SLC9A1 (0.33)
SCHEMBL21021646 0.81 NPC1 (0.35) MEN1ALDH1A1MAPTKMT2A
SCHEMBL20076590 0.77 SLC9A1 (0.34)
SCHEMBL20076606 0.77 MEN1 (0.36) MEN1ALDH1A1MAPTKMT2A
SCHEMBL20076442 0.76 MEN1 (0.38) MEN1ALDH1A1MAPTKMT2A
SCHEMBL21020806 0.76 TP53 (0.30)
SCHEMBL20076512 0.76 PIM1 (0.33)
SCHEMBL20076609 0.75 KMT2A (0.35) MEN1ALDH1A1MAPTKMT2A
SCHEMBL20076539 0.75 NPC1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3283459-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2019-05-22 EP disclosed