Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 5/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11415516 | 0.84 | ACHE (0.42) | ACHEKCNN4SLC22A12ALDH1A1TSHR | |
| SCHEMBL7935323 | 0.81 | ACHE (0.43) | ACHEKCNN4SLC22A12ALDH1A1TSHR | |
| SCHEMBL179259 | 0.81 | ALDH1A1 (0.50) | ACHEKCNN4SLC22A12ALDH1A1TSHR | |
| SCHEMBL7206142 | 0.80 | PDK1 (0.42) | ACHEKCNN4SLC22A12ALDH1A1TSHR | |
| SCHEMBL12764916 | 0.80 | ACHE (0.39) | ACHEKCNN4SLC22A12ALDH1A1TSHR | |
| SCHEMBL27660687 | 0.79 | ALDH1A1 (0.48) | ACHEKCNN4SLC22A12ALDH1A1TSHR | |
| SCHEMBL27726574 | 0.79 | ACHE (0.42) | ACHEKCNN4SLC22A12ALDH1A1TSHR | |
| SCHEMBL169053 | 0.78 | SLC22A12 (0.46) | ACHEKCNN4SLC22A12ALDH1A1TSHR | |
| SCHEMBL29466225 | 0.78 | SLC22A12 (0.46) | ACHEKCNN4SLC22A12ALDH1A1TSHR | |
| SCHEMBL10602905 | 0.78 | KCNN4 (0.42) | ACHEKCNN4SLC22A12ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071327-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2018-04-19 | — | — | WO | disclosed |