SCHEMBL20076640

SCHEMBL20076640

Fc1cc(C2CC2(Cl)Cl)cc(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.31
CYP2C9 P11712 1/20 0.31
TSHR P16473 1/20 0.31
BLM P54132 1/20 0.31
PPARA Q07869 1/20 0.31
KDM1A O60341 1/20 0.30
RCOR1 Q9UKL0 1/20 0.30
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21079011 0.86 KDM1A (0.36) LMNAKDM1ARCOR1
SCHEMBL21079049 0.80 LMNA (0.30) LMNACYP2C9TSHRBLMPPARA
SCHEMBL21079052 0.79
SCHEMBL24281814 0.78 HTR2A (0.41) LMNACYP2C9TSHRBLMPPARA
SCHEMBL8731301 0.75 CES2 (0.30) CES2CES1
SCHEMBL21079081 0.74 KDM1A (0.35) KDM1A
SCHEMBL18154015 0.71 TSHR (0.40) LMNACYP2C9TSHRBLMPPARA
SCHEMBL21019049 0.71 SLC6A4 (0.44) LMNACYP2C9TSHRBLMPPARA
SCHEMBL20076755 0.70 ALDH1A1 (0.38) LMNACYP2C9TSHRBLMPPARA
SCHEMBL21021884 0.70 ALDH1A1 (0.38) LMNACYP2C9TSHRBLMPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3971166-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND COMPOSITIONS, AND PROCESSES, RELATED THERETO Corteva Agriscience LLC (US) 2022-03-23 EP disclosed
WO-2018071327-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-04-19 WO disclosed