Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | CASP1 | P29466 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | THRB | P10828 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964429 | 0.84 | ALDH1A1 (0.52) | ALDH1A1CASP1TSHRCYP3A4PDE10A | |
| SCHEMBL21020629 | 0.83 | ALDH1A1 (0.50) | ALDH1A1CASP1TSHRCYP3A4PDE10A | |
| SCHEMBL17934412 | 0.80 | CYP2D6 (0.46) | ALDH1A1TSHRCYP3A4KDM4EMAPT | |
| SCHEMBL328278 | 0.78 | CASP1 (0.50) | ALDH1A1CASP1TSHRCYP3A4PDE10A | |
| SCHEMBL27825872 | 0.76 | ALDH1A1 (0.44) | ALDH1A1CASP1TSHRCYP3A4PDE10A | |
| SCHEMBL13092437 | 0.76 | ALDH1A1 (0.57) | ALDH1A1CASP1TSHRCYP3A4PDE10A | |
| SCHEMBL2314690 | 0.74 | ALDH1A1 (0.50) | ALDH1A1CASP1TSHRCYP3A4PDE10A | |
| SCHEMBL20076361 | 0.74 | CYP3A4 (0.50) | ALDH1A1CASP1TSHRCYP3A4KDM4E | |
| SCHEMBL2323573 | 0.74 | ALDH1A1 (0.61) | ALDH1A1CASP1TSHRCYP3A4PDE10A | |
| SCHEMBL29783490 | 0.74 | ALDH1A1 (0.61) | ALDH1A1CASP1TSHRCYP3A4PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154966-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | KAMARI PHARMA LTD. (IL) | 2021-08-05 | — | — | WO | disclosed |
| WO-2018071327-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2018-04-19 | — | — | WO | disclosed |