Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | CASP1 | P29466 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20076793 | 0.84 | ALDH1A1 (0.56) | ALDH1A1CASP1TSHRCYP3A4PDE10A | |
| SCHEMBL21020629 | 0.84 | ALDH1A1 (0.50) | ALDH1A1CASP1TSHRCYP3A4PDE10A | |
| SCHEMBL27825872 | 0.78 | ALDH1A1 (0.44) | ALDH1A1CASP1TSHRCYP3A4PDE10A | |
| SCHEMBL23228845 | 0.78 | MAPK14 (0.49) | ALDH1A1CASP1TSHRPDE10AMAPT | |
| SCHEMBL2323573 | 0.76 | ALDH1A1 (0.61) | ALDH1A1CASP1TSHRCYP3A4PDE10A | |
| SCHEMBL2314690 | 0.76 | ALDH1A1 (0.50) | ALDH1A1CASP1TSHRCYP3A4PDE10A | |
| SCHEMBL29783490 | 0.76 | ALDH1A1 (0.61) | ALDH1A1CASP1TSHRCYP3A4PDE10A | |
| SCHEMBL328278 | 0.76 | CASP1 (0.50) | ALDH1A1CASP1TSHRCYP3A4PDE10A | |
| SCHEMBL1321845 | 0.75 | GAA (0.62) | ALDH1A1CASP1TSHRKDM4EMAPT | |
| SCHEMBL6761758 | 0.75 | CASP1 (0.45) | ALDH1A1CASP1TSHRCYP3A4PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835686-B2 | Controlled assembly of charged nanoparticles using functionalized graphene nanomesh | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-09-16 | — | — | US | disclosed |
| US-20130131383-A1 | Controlled Assembly of Charged Nanoparticles Using Functionalized Graphene Nanomesh | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131383-A1 | Controlled Assembly of Charged Nanoparticles Using Functionalized Graphene Nanomesh | STOM, CYTH3, TTN | ALDH1A1 4160/4885CASP1 2237/4885TSHR 1378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.