Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19391220 | 0.77 | KDM4E (0.38) | RAPGEF4KDM4ELMNAALDH1A1MAPT | |
| SCHEMBL27607757 | 0.74 | KDM4E (0.59) | CYP3A4KDM4ELMNAL3MBTL1HTT | |
| SCHEMBL22306213 | 0.74 | KDM4E (0.35) | RAPGEF4KDM4ELMNAALDH1A1MAPT | |
| SCHEMBL22124944 | 0.74 | KDM4E (0.59) | CYP3A4RAPGEF4KDM4ELMNATSHR | |
| SCHEMBL7175355 | 0.74 | KDM4E (0.44) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL6444462 | 0.74 | KDM4E (0.35) | RAPGEF4KDM4ELMNAALDH1A1MAPT | |
| SCHEMBL20076426 | 0.74 | GABRA1 (0.33) | LMNAKMT2AL3MBTL1HTTTSHR | |
| SCHEMBL26120629 | 0.74 | PTGS2 (0.44) | L3MBTL1HTTTSHRMAPTCA1 | |
| SCHEMBL234943 | 0.72 | CYP3A4 (0.58) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL25535106 | 0.72 | CA2 (0.35) | RAPGEF4KDM4ELMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071327-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2018-04-19 | — | — | WO | disclosed |