Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.58 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2548295 | 0.91 | GPR119 (0.52) | FAAHGPR119HPGDKDM4EPKM | |
| SCHEMBL15085741 | 0.89 | GPR119 (0.59) | FAAHGPR119HPGDKDM4EPKM | |
| SCHEMBL544238 | 0.88 | FAAH (0.58) | FAAHGPR119HPGDKDM4EPKM | |
| SCHEMBL13999420 | 0.88 | FAAH (0.58) | FAAHGPR119HPGDKDM4EPKM | |
| SCHEMBL21767510 | 0.88 | GPR119 (0.49) | FAAHGPR119HPGDKDM4EPKM | |
| SCHEMBL21777168 | 0.88 | GPR119 (0.49) | FAAHGPR119HPGDKDM4EPKM | |
| SCHEMBL21767508 | 0.88 | GPR119 (0.49) | FAAHGPR119HPGDKDM4EPKM | |
| SCHEMBL3478015 | 0.87 | FAAH (0.57) | FAAHGPR119HPGDKDM4EPKM | |
| SCHEMBL16921334 | 0.86 | NR1H2 (0.51) | FAAHGPR119HPGD | |
| SCHEMBL6794692 | 0.85 | FAAH (0.56) | FAAHGPR119HPGDKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10894775-B2 | Piperidine derivatives as liver X receptor beta agonists, compositions, and their use | MERCK SHARP & DOHME CORP. (US) | 2021-01-19 | — | — | US | disclosed |
| WO-2018071315-A2 | PIPERIDINE DERIVATIVES AS LIVER X RECEPTOR BETA AGONISTS, COMPOSITIONS, AND THEIR USE | MERCK SHARP & DOHME CORP. (US) | 2018-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10894775-B2 | Piperidine derivatives as liver X receptor beta agonists, compositions, and their use | NR1H2, NR1H3, ADRB1 | FAAH 1242/4885GPR119 7/4885HPGD 2120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.