Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23143030 | 0.83 | MAPT (0.39) | GAAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL18930558 | 0.83 | CTSS (0.48) | CTSSCTSKGAAALDH1A1LMNA | |
| SCHEMBL12401314 | 0.83 | TSHR (0.35) | ALDH1A1TSHRSMN1; SMN2KDM4EMAPT | |
| SCHEMBL12018961 | 0.81 | ALDH1A1 (0.43) | CTSSCTSKGAAALDH1A1LMNA | |
| SCHEMBL13603010 | 0.81 | ALDH1A1 (0.43) | CTSSCTSKGAAALDH1A1LMNA | |
| SCHEMBL12562326 | 0.81 | ALDH1A1 (0.43) | CTSSCTSKGAAALDH1A1LMNA | |
| SCHEMBL14347466 | 0.80 | CTSS (0.38) | CTSSCTSKGAAALDH1A1LMNA | |
| SCHEMBL23065777 | 0.80 | CTSS (0.38) | CTSSCTSKGAAALDH1A1LMNA | |
| SCHEMBL12229210 | 0.79 | KDM4E (0.39) | CTSSCTSKGAAALDH1A1TSHR | |
| SCHEMBL109682 | 0.79 | LMNA (0.55) | ALDH1A1LMNAUSP2MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951001-B2 | Hepatoprotectant acetaminophen mutual prodrugs | ACORDA THERAPEUTICS, INC. (US) | 2018-04-24 | — | — | US | disclosed |