Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20079368 | 0.85 | ALDH1A1 (0.47) | ALDH1A1HPGDMAPTTHRBL3MBTL1 | |
| SCHEMBL18358721 | 0.81 | PSMB8 (0.49) | HPGDMAPTTHRBTDP1PGR | |
| SCHEMBL20079386 | 0.81 | PGR (0.54) | PGRPOLBDAO | |
| SCHEMBL20079416 | 0.79 | ALDH1A1 (0.42) | ALDH1A1HPGDMAPTTHRBL3MBTL1 | |
| SCHEMBL20079373 | 0.72 | ALDH1A1 (0.44) | ALDH1A1HPGDMAPTTHRBL3MBTL1 | |
| SCHEMBL18358722 | 0.69 | PSMB8 (0.50) | ALDH1A1HPGDMAPTTHRBPGR | |
| SCHEMBL20656265 | 0.68 | ALDH1A1 (0.43) | ALDH1A1HPGDMAPTTHRBL3MBTL1 | |
| SCHEMBL20079380 | 0.66 | DAO (0.58) | ALDH1A1L3MBTL1PGRPOLBDAO | |
| SCHEMBL18358717 | 0.65 | PSMB8 (0.45) | ALDH1A1HPGDPGRKDM4EPSMB8 | |
| SCHEMBL16883537 | 0.65 | DAO (0.49) | PGRKDM4EDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951046-B2 | TRPA1 modulators | ALGOMEDIX, INC. (US) | 2018-04-24 | — | — | US | disclosed |