Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20079376 | 0.84 | PGR (0.43) | ALDH1A1HPGDL3MBTL1MAPTTHRB | |
| SCHEMBL20079416 | 0.84 | ALDH1A1 (0.42) | ALDH1A1HPGDL3MBTL1MAPTTHRB | |
| SCHEMBL20079375 | 0.81 | ALDH1A1 (0.51) | ALDH1A1HPGDL3MBTL1MAPTTHRB | |
| SCHEMBL20079374 | 0.72 | ALDH1A1 (0.55) | ALDH1A1HPGDL3MBTL1MAPTTHRB | |
| SCHEMBL18358723 | 0.70 | PSMB8 (0.44) | ALDH1A1HPGDPGRARPSMB8 | |
| SCHEMBL20079372 | 0.70 | PGR (0.49) | ALDH1A1HPGDL3MBTL1MAPTTHRB | |
| SCHEMBL20079368 | 0.69 | ALDH1A1 (0.47) | ALDH1A1HPGDL3MBTL1MAPTTHRB | |
| SCHEMBL20079377 | 0.68 | ALDH1A1 (0.46) | ALDH1A1HPGDL3MBTL1MAPTTHRB | |
| SCHEMBL18358724 | 0.67 | PSMB8 (0.44) | ALDH1A1HPGDL3MBTL1MAPTPGR | |
| SCHEMBL25433823 | 0.67 | PGR (0.43) | MAPTTHRBPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10428049-B2 | TRPA1 modulators | ALGOMEDIX, INC. (US) | 2019-10-01 | — | — | US | disclosed |
| US-20190016701-A1 | TRPA1 MODULATORS | ALGOMEDIX, INC. (US) | 2019-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10428049-B2 | TRPA1 modulators | TRPA1, TRPV1, TRPV2 | ALDH1A1 1436/4885HPGD 1797/4885L3MBTL1 2330/4885 |
| US-20190016701-A1 | TRPA1 MODULATORS | TRPA1, TRPV1, TRPV2 | ALDH1A1 1436/4885HPGD 1797/4885L3MBTL1 2330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.