⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12019481 | 0.81 | L3MBTL1 (0.30) | — | |
| SCHEMBL20466942 | 0.75 | PER2 (0.35) | — | |
| SCHEMBL266558 | 0.71 | — | — | |
| SCHEMBL25668851 | 0.69 | L3MBTL1 (0.36) | — | |
| SCHEMBL24731109 | 0.65 | TSHR (0.38) | — | |
| SCHEMBL22541564 | 0.65 | TSHR (0.38) | — | |
| SCHEMBL4338609 | 0.65 | TSHR (0.38) | — | |
| SCHEMBL29348305 | 0.62 | — | — | |
| SCHEMBL25773846 | 0.62 | — | — | |
| SCHEMBL24287634 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |
| US-9951046-B2 | TRPA1 modulators | ALGOMEDIX, INC. (US) | 2018-04-24 | — | — | US | disclosed |