Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17988490 | 0.88 | SMN1; SMN2 (0.45) | SMN1; SMN2 | |
| SCHEMBL23139484 | 0.87 | S1PR1 (0.59) | S1PR1SMN1; SMN2RORC | |
| SCHEMBL17014550 | 0.83 | GAA (0.58) | S1PR1RORC | |
| SCHEMBL23139488 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2 | |
| SCHEMBL9633496 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2RORC | |
| SCHEMBL24599224 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2 | |
| SCHEMBL14159036 | 0.75 | CA1 (0.46) | SMN1; SMN2 | |
| SCHEMBL23139483 | 0.73 | RORC (0.56) | S1PR1SMN1; SMN2RORC | |
| SCHEMBL7217455 | 0.72 | LPAR1 (0.35) | — | |
| SCHEMBL13122826 | 0.71 | RORC (0.59) | S1PR1SMN1; SMN2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951071-B2 | Dihydropyridone P1 as factor XIa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-04-24 | — | — | US | disclosed |