Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CFTR | P13569 | 2/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17988490 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2CFTRMAPTKDM4ECYP2D6 | |
| SCHEMBL9864529 | 0.78 | TGM2 (0.56) | CFTRNR1H4TRPV1GAA | |
| SCHEMBL11518967 | 0.77 | ALDH1A1 (0.58) | SMN1; SMN2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL20079586 | 0.76 | S1PR1 (0.46) | SMN1; SMN2 | |
| SCHEMBL7284429 | 0.76 | TUBB4A (0.59) | SMN1; SMN2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7454764 | 0.75 | KMT2A (0.59) | SMN1; SMN2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL613429 | 0.75 | SMN1; SMN2 (0.76) | SMN1; SMN2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL23139488 | 0.73 | SMN1; SMN2 (0.49) | SMN1; SMN2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9609808 | 0.73 | SMN1; SMN2 (0.82) | SMN1; SMN2MAPTPOLBKDM4ECYP2D6 | |
| SCHEMBL2054672 | 0.73 | SMN1; SMN2 (0.62) | SMN1; SMN2MAPTMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220211855-A1 | THERAPEUTIC CONJUGATES | TOTUS MEDICINES INC. | 2022-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220211855-A1 | THERAPEUTIC CONJUGATES | CD47, CD44, EPCAM | SMN1; SMN2 620/4885CFTR 1431/4885TUBB4A 271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.