Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27298280 | 0.73 | HPGD (0.46) | — | |
| SCHEMBL17988490 | 0.72 | SMN1; SMN2 (0.45) | GAACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20079586 | 0.72 | S1PR1 (0.46) | — | |
| SCHEMBL4826143 | 0.71 | SMN1; SMN2 (0.38) | GAATSHR | |
| SCHEMBL7225330 | 0.71 | NLRP3 (0.50) | CYP1A2CYP2C9TSHRCYP2C19 | |
| SCHEMBL18415575 | 0.70 | GPR35 (0.43) | GAATSHR | |
| SCHEMBL13452000 | 0.69 | RARG (0.37) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL28143738 | 0.69 | CYP2C9 (0.47) | GAACYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL31593161 | 0.69 | CYP1A2 (0.57) | GAACYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL31593162 | 0.69 | CYP1A2 (0.57) | GAACYP1A2CYP3A4CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | claimed |