Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20079689 | 0.91 | KMT2A (0.50) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20079665 | 0.73 | HDAC1 (0.48) | SMN1; SMN2 | |
| SCHEMBL10114146 | 0.71 | RXFP1 (0.70) | TP53ALDH1A1KDM4ERXFP1 | |
| SCHEMBL14754445 | 0.71 | RAB9A (0.49) | POLBMAPTTP53ALDH1A1MEN1 | |
| SCHEMBL20079645 | 0.70 | CYP11B2 (0.44) | MAPTTP53MEN1KMT2A | |
| SCHEMBL19036473 | 0.69 | YTHDC1 (0.44) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9010469 | 0.69 | IKBKB (0.36) | TP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL20079722 | 0.69 | YTHDC1 (0.45) | POLBL3MBTL1MAPTTP53ALDH1A1 | |
| SCHEMBL9312707 | 0.68 | POLB (1.00) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10113854 | 0.67 | RXFP1 (0.74) | TP53ALDH1A1KDM4ERXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951073-B2 | Compounds and compositions for treating chemical warfare agent-induced injuries | HYDRA BIOSCIENCES, INC. (US) | 2018-04-24 | — | — | US | disclosed |