SCHEMBL2007985

SCHEMBL2007985

CCCCCC(OC(=O)c1ccccc1)OC(=O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
ALDH1A1 P00352 1/20 0.51
LMNA P02545 2/20 0.50
TSHR P16473 4/20 0.49
TP53 P04637 2/20 0.49
CNR2 P34972 1/20 0.48
CES2 O00748 3/20 0.47
CES1 P23141 3/20 0.47
CTSK P43235 1/20 0.47
PRSS1 P07477 3/20 0.47
CTSG P08311 2/20 0.47
CTRB1 P17538 2/20 0.47
CMA1 P23946 2/20 0.47
PRSS2 P07478 1/20 0.46
PRSS3 P35030 1/20 0.46
ALOX12 P18054 1/20 0.45
NAAA Q02083 1/20 0.45
TDP1 Q9NUW8 1/20 0.44
PDCD1 Q15116 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29608632 0.98 ALDH1A1 (0.54) MEN1KMT2AALDH1A1LMNATSHR
SCHEMBL29669582 0.98 ALDH1A1 (0.54) MEN1KMT2AALDH1A1LMNATSHR
SCHEMBL28035571 0.95 MEN1 (0.53) MEN1KMT2AALDH1A1LMNATSHR
SCHEMBL15902930 0.93 ALDH1A1 (0.49) MEN1KMT2AALDH1A1LMNATSHR
SCHEMBL5155751 0.93 ESR1 (0.51) MEN1KMT2AALDH1A1LMNATSHR
SCHEMBL28389216 0.92 MEN1 (0.52) MEN1KMT2AALDH1A1LMNATSHR
SCHEMBL5155882 0.91 ESR1 (0.50) MEN1KMT2AALDH1A1LMNATSHR
SCHEMBL5153682 0.91 ESR1 (0.50) MEN1KMT2AALDH1A1LMNATSHR
SCHEMBL15903015 0.91 ALDH1A1 (0.48) MEN1KMT2AALDH1A1LMNATSHR
SCHEMBL28389221 0.91 MEN1 (0.51) MEN1KMT2AALDH1A1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011071674-A1 ASYMMETRIC CYCLIC DIESTER COMPOUNDS FERRO CORPORATION (US) 2011-06-16 WO claimed
US-20100113664-A1 Asymmetric Cyclic Diester Compounds FERRO CORPORATION (US) 2010-05-06 US claimed
EP-1395232-B1 COSMETIC COMPOSITION FOR NAILS, FREE OF PHTHALATES, CAMPHOR AND AROMATIC SOLVENT FIABILA (FR) 2006-10-18 EP claimed
US-20030152535-A1 Cosmetic composition for nails, free of phthalates, camphor and aromatic solvent FIABILA (FR) 2003-08-14 US claimed
US-8679465-B2 Cosmetic composition for nails, free of phthalates, camphor and aromatic solvent FIABILA (FR) 2014-03-25 US disclosed
WO-2011071674-A1 ASYMMETRIC CYCLIC DIESTER COMPOUNDS FERRO CORPORATION (US) 2011-06-16 WO disclosed
US-20100113664-A1 Asymmetric Cyclic Diester Compounds FERRO CORPORATION (US) 2010-05-06 US disclosed
US-7388061-B2 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-06-17 US disclosed
US-20050239636-A1 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-10-27 US disclosed
US-20030152535-A1 Cosmetic composition for nails, free of phthalates, camphor and aromatic solvent FIABILA (FR) 2003-08-14 US disclosed
EP-0034337-B1 A PROCESS FOR THE OPTICAL RESOLUTION OF A RACEMIC MIXTURE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1984-10-24 EP disclosed
US-4259225-A STORAGE STABILITY DAINIPPON INK & CHEMICALS, INC. (JP) 1981-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030152535-A1 Cosmetic composition for nails, free of phthalates, camphor and aromatic solvent PIK3C3, POLR1C, CECR2 MEN1 2752/4885KMT2A 1358/4885ALDH1A1 3306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.