SCHEMBL2007995

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2742797	0.92	CYP3A4 (0.43)	CYP3A4USP2PPARGPPARDFFAR1
	SCHEMBL19418882	0.83	CYP3A4 (0.54)	CYP3A4USP2MAPTMAPK1TDP1
	SCHEMBL12946428	0.82	CYP3A4 (0.47)	CYP3A4USP2PPARGPPARDFFAR1
	SCHEMBL24288953	0.81	CA2 (0.54)	PPARGPPARDFFAR1ESR1ESR2
	SCHEMBL5854087	0.80	PPARG (0.40)	CYP3A4USP2PPARGPPARDFFAR1
	SCHEMBL12914758	0.79	CA2 (0.50)	CYP3A4USP2FFAR1ESR1ESR2
	SCHEMBL2070035	0.77	CYP3A4 (0.53)	CYP3A4USP2ESR1ESR2MAPT
	SCHEMBL7500860	0.77	CYP3A4 (0.53)	CYP3A4USP2ESR1ESR2MAPT
	SCHEMBL2070036	0.77	CYP3A4 (0.53)	CYP3A4USP2ESR1ESR2MAPT
	SCHEMBL19418887	0.77	CYP3A4 (0.45)	CYP3A4USP2PPARGPPARDFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.