Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15444698 | 0.85 | HTR3A (0.57) | HTR3AKMT2AL3MBTL1LMNAALDH1A1 | |
| SCHEMBL23794575 | 0.85 | HTR3A (0.57) | HTR3AALDH1A1MAPTPOLB | |
| Hydrochloric Acid SCHEMBL15420906 | 0.84 | HTR3A (0.56) | HTR3AALDH1A1MAPTPOLB | |
| SCHEMBL15440795 | 0.82 | HTR3A (0.57) | HTR3AKMT2AL3MBTL1TSHRMEN1 | |
| SCHEMBL20080348 | 0.79 | KMT2A (0.52) | HTR3AKMT2AL3MBTL1TSHRMEN1 | |
| SCHEMBL20080419 | 0.77 | HTR3A (0.55) | HTR3AKMT2AL3MBTL1TSHRMEN1 | |
| SCHEMBL19068175 | 0.77 | HTR3A (0.53) | HTR3AKMT2AL3MBTL1TSHRMEN1 | |
| SCHEMBL19969879 | 0.76 | HTR3A (0.54) | HTR3AKMT2AL3MBTL1TSHRMEN1 | |
| SCHEMBL23812575 | 0.75 | KMT2A (0.53) | HTR3AKMT2AL3MBTL1TSHRMEN1 | |
| SCHEMBL4106159 | 0.74 | KMT2A (0.73) | HTR3AKMT2AL3MBTL1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312169-A1 | 5-HT3 RECEPTOR ANTAGONISTS | Takeda Pharmaceutical Company Limited (JP) | 2018-04-25 | — | — | EP | disclosed |