SCHEMBL20080909

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Hydrochloric Acid SCHEMBL28913555	0.98	DRD2 (0.42)	DRD2DRD3ARKDRPARP1
	SCHEMBL28329104	0.79	FLT3 (0.43)	DRD2DRD3ARKDRPARP1
	SCHEMBL6909902	0.72	ADRB1 (0.47)	DRD2DRD3ADRB1HTR3EHTR3B
	SCHEMBL81908	0.72	ADRB1 (0.47)	DRD2DRD3ADRB1HTR3EHTR3B
	Hydrochloric Acid SCHEMBL27237952	0.70	ADRB1 (0.46)	DRD2DRD3ADRB1HTR3EHTR3B
	SCHEMBL17014878	0.70	AR (0.67)	ARALDH1A1KMT2A
	SCHEMBL1432603	0.69	AOC3 (0.40)	ADRB1HTR3EHTR3BHTR3AHTR3D
	Hydrochloric Acid SCHEMBL4590342	0.69	KDR (0.53)	DRD2DRD3KDRPARP1TNK1
	SCHEMBL2828462	0.69	KDR (0.53)	DRD2DRD3KDRPARP1TNK1
	SCHEMBL22769076	0.68	ADRB1 (0.43)	ADRB1HTR3EHTR3BHTR3AHTR3D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.