Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 7/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 5/20 | 0.47 |
| ▸ | HTR3B | O95264 | 5/20 | 0.47 |
| ▸ | HTR3A | P46098 | 5/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 5/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 5/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | BPTF | Q12830 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27237952 | 0.98 | ADRB1 (0.46) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL29999306 | 0.85 | MAPT (0.39) | ALDH1A1CYP2D6HTTMEN1HPGD | |
| SCHEMBL81908 | 0.76 | ADRB1 (0.47) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL2247749 | 0.75 | ALDH1A1 (0.43) | ALDH1A1HTR2CTP53KMT2A | |
| SCHEMBL1432603 | 0.73 | AOC3 (0.40) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL20080909 | 0.72 | DRD2 (0.44) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL22769076 | 0.72 | ADRB1 (0.43) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Hydrochloric Acid SCHEMBL28913555 | 0.71 | DRD2 (0.42) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL27237972 | 0.71 | MAPT (0.50) | ALDH1A1HTTMEN1HPGDKMT2A | |
| SCHEMBL3851321 | 0.69 | KDM4E (0.39) | ADRB1HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011608-A1 | REGULATOR CONTAINING TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海枢境生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |
| CN-113292514-B | Piperazine derivative and organic photoelectric device comprising same | 浙江华显光电科技有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-113292514-A | Piperazine derivative and organic photoelectric device comprising same | 浙江华显光电科技有限公司 | 2021-08-24 | — | — | CN | disclosed |
| US-6825200-B1 | TREATING, PROLONGING, OR EXTENDING THE ONSET OF ORGAN REJECTION IN A HUMAN DURING OR AFTER ORGAN TRANSPLANTATION IN A HUMAN | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1226159-A1 | SUBSTITUTED DIPEPTIDES HAVING NOS INHIBITING ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001032690-A1 | SUBSTITUTED DIPEPTIDES HAVING NOS INHIBITING ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-10 | — | — | WO | disclosed |