SCHEMBL2008131

SCHEMBL2008131

Fc1ccc(CCl)c(F)n1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9899335 0.79 KMT2A (0.34) KMT2A
SCHEMBL31361113 0.79 KMT2A (0.34) KMT2A
SCHEMBL8222640 0.76 GABRA1 (0.31)
SCHEMBL21327044 0.76 CCR1 (0.30)
SCHEMBL22750094 0.76 LOXL2 (0.39)
SCHEMBL2212306 0.76 KDM4E (0.31)
SCHEMBL29773921 0.76 KDM4E (0.31)
SCHEMBL5325637 0.73 TDP1 (0.30)
SCHEMBL5871112 0.73 SIRT2 (0.31)
SCHEMBL24468400 0.71 MCL1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015047124-A1 NOVEL CHEMICAL COMPOUNDS DERIVED FROM 2,4-DIAMINO-1,3,5-TRIAZINE FOR THE PROPHYLAXIS AND TREATMENT OF HUMAN AND ANIMAL DISEASES Общество с ограниченной ответственностью "Молекулярные Технологии" 2015-04-02 WO disclosed
EP-2535327-A1 Insecticidal 3-acylaminobenzanilides Bayer CropScience AG (DE) 2012-12-19 EP disclosed
US-7964735-B2 Insecticidal 3-acylaminobenzanilides BAYER CROPSCIENCE AG (DE) 2011-06-21 US disclosed
US-7799738-B2 Insecticidal 2-acylaminothiazole-4-carboxamides BAYER CROPSCIENCE AG (DE) 2010-09-21 US disclosed
US-20090215623-A1 Insecticidal 3-acylaminobenzanilides BAYER CROPSCIENCE AG (DE) 2009-08-27 US disclosed
US-20080300136-A1 Insecticidal 2-Acylaminothiazole-4-Carboxamides BAYER CROPSCIENCE AG (DE) 2008-12-04 US disclosed
EP-1963290-A1 INSECTICIDAL 2 -ACYLAMINOTHIAZOLE-4 -CARBOXAMIDES Bayer CropScience Aktiengesellschaft (DE) 2008-09-03 EP disclosed
EP-1912933-A1 INSECTICIDAL 3-ACYLAMINOBENZANILIDES Bayer CropScience AG (DE) 2008-04-23 EP disclosed
WO-2007051560-A1 INSECTICIDAL 2 -ACYLAMINOTHIAZOLE-4 -CARBOXAMIDES BAYER CROPSCIENCE AG (DE) 2007-05-10 WO disclosed
WO-2007017075-A1 INSECTICIDAL 3-ACYLAMINOBENZANILIDES BAYER CROPSCIENCE AG (DE) 2007-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080300136-A1 Insecticidal 2-Acylaminothiazole-4-Carboxamides AADAC, HDHD5, HRH4 KMT2A 426/4885
US-20090215623-A1 Insecticidal 3-acylaminobenzanilides CBR3, AADAC, DDT KMT2A 1245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.