Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 3/20 | 0.48 |
| ▸ | RBP4 | P02753 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2010567 | 0.86 | KLKB1 (0.43) | KLKB1RBP4KDM4CKDM5AKDM5B | |
| SCHEMBL16690901 | 0.78 | RBP4 (0.54) | KLKB1RBP4KDM4CKDM5AKDM5B | |
| SCHEMBL3688462 | 0.77 | KDM4C (0.57) | KLKB1RBP4KDM4CKDM5AKDM5B | |
| SCHEMBL1479335 | 0.77 | NAPRT (0.48) | KLKB1RBP4KDM4CKDM5AKDM5B | |
| SCHEMBL1479212 | 0.77 | NAPRT (0.48) | KLKB1RBP4KDM4CKDM5AKDM5B | |
| SCHEMBL12510626 | 0.76 | SIRT2 (0.36) | CYP3A4CYP2C9NPC1RAB9A | |
| SCHEMBL24310337 | 0.76 | KDM4C (0.50) | KLKB1RBP4KDM4CKDM5AKDM5B | |
| SCHEMBL24310642 | 0.75 | KDM4C (0.52) | KLKB1RBP4KDM4CKDM5AKDM5B | |
| SCHEMBL28146943 | 0.75 | SIRT2 (0.36) | CYP3A4CYP2C9NPC1RAB9A | |
| SCHEMBL15964744 | 0.75 | RBP4 (0.54) | KLKB1RBP4KDM4CKDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011070069-A1 | PROCESS FOR PREPARATION OF MEDETOMIDINE | I-TECH AB (SE) | 2011-06-16 | — | — | WO | claimed |
| WO-2011070069-A1 | PROCESS FOR PREPARATION OF MEDETOMIDINE | I-TECH AB (SE) | 2011-06-16 | — | — | WO | disclosed |
| WO-2011070069-A1 | PROCESS FOR PREPARATION OF MEDETOMIDINE | I-TECH AB (SE) | 2011-06-16 | — | — | WO | disclosed |