Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | KARS1 | Q15046 | 4/20 | 0.81 |
| ▸ | RXRA | P19793 | 1/20 | 0.81 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.81 |
| ▸ | CDK2 | P24941 | 1/20 | 0.81 |
| ▸ | RXRB | P28702 | 1/20 | 0.81 |
| ▸ | RXRG | P48443 | 1/20 | 0.81 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.65 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.65 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.65 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2989705 | 1.00 | CYP3A4 (1.00) | CYP3A4LMNAKARS1RXRACCNE1 | |
| SCHEMBL14479889 | 1.00 | CYP3A4 (1.00) | CYP3A4LMNAKARS1RXRACCNE1 | |
| SCHEMBL30383762 | 1.00 | CYP3A4 (1.00) | CYP3A4LMNAKARS1RXRACCNE1 | |
| Dehydroabietic Acid SCHEMBL7939559 | 0.90 | CYP3A4 (0.82) | CYP3A4LMNAKARS1RXRACCNE1 | |
| Dehydroabietic Acid SCHEMBL18019015 | 0.90 | KARS1 (1.00) | CYP3A4LMNAKARS1RXRACCNE1 | |
| Dehydroabietic Acid SCHEMBL15744753 | 0.90 | KARS1 (1.00) | CYP3A4LMNAKARS1RXRACCNE1 | |
| Dehydroabietic Acid SCHEMBL14653170 | 0.90 | KARS1 (1.00) | CYP3A4LMNAKARS1RXRACCNE1 | |
| Dehydroabietic Acid SCHEMBL2603437 | 0.90 | KARS1 (1.00) | CYP3A4LMNAKARS1RXRACCNE1 | |
| Dehydroabietic Acid SCHEMBL15313390 | 0.90 | KARS1 (1.00) | CYP3A4LMNAKARS1RXRACCNE1 | |
| Dehydroabietic Acid SCHEMBL19798161 | 0.90 | KARS1 (1.00) | CYP3A4LMNAKARS1RXRACCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118026940-A | Tetra-substituted diene compound and preparation method and application thereof | 泽同制药(江阴)有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-117924192-A | Conjugated olefin derivative and preparation method and application thereof | 杭州师范大学 | 2024-04-26 | — | — | CN | claimed |
| US-20230074763-A1 | IDENTIFICATION OF HOST-TARGETING MODULATORS OF BACTERIAL UPTAKE AND ASSAY FOR QUANTIFYING INTRACELLULAR BACTERIA | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2023-03-09 | — | — | US | claimed |
| US-20230003721-A1 | MITOTHERAPEUTICS FOR THE TREATMENT OF BRAIN DISORDERS | THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2023-01-05 | — | — | US | claimed |
| CN-115073294-A | Method for synthesizing axial chiral aryl conjugated diene through asymmetric alfa-C-H olefination reaction and product thereof | 杭州师范大学 | 2022-09-20 | — | — | CN | claimed |
| EP-3808348-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY (PML) | Biogen MA Inc. (US) | 2021-04-21 | — | — | EP | claimed |
| CN-110713445-B | Preparation and application of rosin-based chiral worm micelle | 江南大学 | 2020-09-04 | — | — | CN | claimed |
| CN-108503732-B | Dehydroabietyl amide internal plasticization PVC material and preparation method thereof | 中国林业科学研究院林产化学工业研究所 | 2020-06-30 | — | — | CN | claimed |
| CN-111111549-A | Dehydroabietyl-based saccharide surfactant and preparation method and application thereof | 广东省石油与精细化工研究院 | 2020-05-08 | — | — | CN | claimed |
| US-10583099-B2 | Isotope enhanced ambroxol for long lasting autophagy induction | UNM RAINFOREST INNOVATIONS | 2020-03-10 | — | — | US | claimed |
| CN-110713445-A | Preparation and application of rosin-based chiral worm micelle | 江南大学 | 2020-01-21 | — | — | CN | claimed |
| CN-110485199-A | Dehydroabietic acid lignin emulsifier and the AKD lotion prepared with the emulsifier | SHANDONG DONGSHENG NEW MAT CO | 2019-11-22 | — | — | CN | claimed |
| US-20190269806-A1 | ISOTOPE ENHANCED AMBROXOL FOR LONG LASTING AUTOPHAGY INDUCTION | UNM RAINFOREST INNOVATIONS | 2019-09-05 | — | — | US | claimed |
| CN-108503732-A | Dehydrogenation fir base amide internal plasticization PVC material and preparation method thereof | 中国林业科学研究院林产化学工业研究所 | 2018-09-07 | — | — | CN | claimed |
| US-20130183289-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY (PML) | BIOGEN IDEC MA INC (US) | 2013-07-18 | — | — | US | claimed |
| CN-102086299-A | Transparent crystallization polylactic acid plastic and preparation method thereof | NINGBO INST MAT TECH & ENG CAS | 2011-06-08 | — | — | CN | claimed |
| EP-2200611-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY (PML) | Biogen Idec MA, Inc. (US) | 2010-06-30 | — | — | EP | claimed |
| WO-2009038684-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY (PML) | BIOGEN IDEC MA INC. (US) | 2009-03-26 | — | — | WO | claimed |
| US-7427324-B1 | Methods of making quinacridone nanoscale pigment particles | XEROX CORPORATION (US) | 2008-09-23 | — | — | US | claimed |
| EP-1163210-B1 | ROSIN AMINE ANTI-FOULING AGENTS | BAYER CHEMICALS AG (DE) | 2004-02-04 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190269806-A1 | ISOTOPE ENHANCED AMBROXOL FOR LONG LASTING AUTOPHAGY INDUCTION | BECN1, RABGGTB, TFEB | CYP3A4 1112/4885LMNA 3770/4885KARS1 2296/4885 |
| US-10583099-B2 | Isotope enhanced ambroxol for long lasting autophagy induction | BECN1, TFEB, ATG7 | CYP3A4 776/4885LMNA 3419/4885KARS1 3012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.