Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMKK1 | Q8N5S9 | 2/20 | 0.32 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20083187 | 0.93 | CAMKK1 (0.32) | CAMKK1CAMKK2RORC | |
| SCHEMBL20083145 | 0.88 | CAMKK1 (0.30) | CAMKK1CAMKK2 | |
| SCHEMBL1290284 | 0.88 | CAMKK2 (0.34) | CAMKK1CAMKK2RORC | |
| SCHEMBL20083185 | 0.87 | BRD4 (0.36) | CAMKK1CAMKK2 | |
| SCHEMBL1289936 | 0.87 | RORC (0.35) | CAMKK1CAMKK2RORC | |
| SCHEMBL20083172 | 0.86 | KDM4E (0.34) | CAMKK1CAMKK2 | |
| SCHEMBL20083210 | 0.86 | KDM4E (0.34) | CAMKK1CAMKK2 | |
| SCHEMBL1290126 | 0.86 | NOTUM (0.34) | CAMKK1CAMKK2RORC | |
| SCHEMBL19723472 | 0.86 | CAMKK2 (0.35) | CAMKK1CAMKK2 | |
| SCHEMBL19174466 | 0.85 | KDM4E (0.32) | CAMKK1CAMKK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3476844-A1 | ANTIMICROBIAL 4-OXOQUINOLIZINES | Emergent Product Development Gaithersburg Inc. (US) | 2019-05-01 | — | — | EP | disclosed |
| EP-3312176-A1 | ANTIMICROBIAL 4-OXOQUINOLIZINES | Emergent Product Development Gaithersburg Inc. (US) | 2018-04-25 | — | — | EP | disclosed |