Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.30 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20083174 | 0.88 | CAMKK1 (0.32) | CAMKK1CAMKK2 | |
| SCHEMBL12501938 | 0.82 | ALOX5AP (0.45) | CAMKK1CAMKK2KDM4E | |
| SCHEMBL20083187 | 0.81 | CAMKK1 (0.32) | CAMKK1CAMKK2 | |
| SCHEMBL5432203 | 0.79 | PDE4D (0.36) | — | |
| SCHEMBL1289914 | 0.78 | PIK3CA (0.36) | CAMKK1CAMKK2KDM4E | |
| SCHEMBL20083221 | 0.78 | RORC (0.33) | CAMKK2 | |
| SCHEMBL6673956 | 0.77 | CAMKK1 (0.30) | CAMKK1CAMKK2 | |
| SCHEMBL12502230 | 0.77 | MAPK14 (0.39) | — | |
| SCHEMBL20083185 | 0.76 | BRD4 (0.36) | CAMKK1CAMKK2 | |
| SCHEMBL1290284 | 0.76 | CAMKK2 (0.34) | CAMKK1CAMKK2KDM4EGFERKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3476844-A1 | ANTIMICROBIAL 4-OXOQUINOLIZINES | Emergent Product Development Gaithersburg Inc. (US) | 2019-05-01 | — | — | EP | disclosed |
| EP-3312176-A1 | ANTIMICROBIAL 4-OXOQUINOLIZINES | Emergent Product Development Gaithersburg Inc. (US) | 2018-04-25 | — | — | EP | disclosed |