Sugi Predict

Sugi Predict / Compounds / SCHEMBL20083802

SCHEMBL20083802

SCHEMBL20083802

ICCn1ncc2ccccc21

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 1/20 0.62
▸ KMO O15229 1/20 0.60
▸ RECQL P46063 2/20 0.58
▸ DAO P14920 1/20 0.50
▸ P2RX7 Q99572 1/20 0.47
▸ ADRA2A P08913 1/20 0.45
▸ POLB P06746 3/20 0.43
▸ HSD17B10 Q99714 2/20 0.43
▸ L3MBTL1 Q9Y468 2/20 0.43
▸ HTR2A P28223 1/20 0.40
▸ HTR2C P28335 1/20 0.40
▸ HTR2B P41595 1/20 0.40
▸ NPC1 O15118 3/20 0.40
▸ RAB9A P51151 3/20 0.40
▸ TSHR P16473 3/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27997802 0.82 RECQL (0.65) CYP1A2KMORECQLDAOP2RX7
SCHEMBL14578726 0.81 KMO (0.65) CYP1A2KMORECQLDAOP2RX7
SCHEMBL731073 0.81 CYP1A2 (0.62) CYP1A2KMORECQLDAOP2RX7
SCHEMBL8768618 0.81 CYP1A2 (0.62) CYP1A2KMORECQLDAOP2RX7
SCHEMBL29947768 0.81 CYP1A2 (0.62) CYP1A2KMORECQLDAOP2RX7
SCHEMBL20083662 0.81 CYP1A2 (0.62) CYP1A2KMORECQLDAOP2RX7
SCHEMBL5565705 0.81 CYP1A2 (0.62) CYP1A2KMORECQLDAOP2RX7
SCHEMBL20083661 0.81 CYP1A2 (0.62) CYP1A2KMORECQLDAOP2RX7
SCHEMBL31429458 0.81 KMO (0.65) CYP1A2KMORECQLDAOP2RX7
SCHEMBL29487638 0.81 CYP1A2 (0.62) CYP1A2KMORECQLDAOP2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11192907-B2 Aminopeptidase A inhibitors and pharmaceutical compositions comprising the same QUANTUM GENOMICS (FR) 2021-12-07 — — US disclosed
US-20210309678-A1 AMINOPEPTIDASE A INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME Institut National de la Santé et de la Recherche Médicale (FR) 2021-10-07 — — US disclosed
CN-113166182-A Aminopeptidase A inhibitor and pharmaceutical composition comprising the same 量子基因公司 2021-07-23 — — CN disclosed
EP-2563123-B1 NOVEL BETA 3 ADRENERGIC RECEPTOR AGONISTS MERCK SHARP & DOHME (US) 2018-04-25 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11192907-B2 Aminopeptidase A inhibitors and pharmaceutical compositions comprising the same ANPEP, DNPEP, ENPEP CYP1A2 3100/4885KMO 2095/4885RECQL 1702/4885
US-20210309678-A1 AMINOPEPTIDASE A INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME ANPEP, DNPEP, ENPEP CYP1A2 3100/4885KMO 2095/4885RECQL 1702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.