Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14578726 | 1.00 | KMO (0.65) | KMOCYP1A2RECQLDAOP2RX7 | |
| SCHEMBL4951648 | 0.89 | KMO (0.61) | KMOCYP1A2RECQLDAOP2RX7 | |
| SCHEMBL5365409 | 0.87 | KMO (0.59) | KMOCYP1A2RECQLDAOP2RX7 | |
| SCHEMBL31646798 | 0.86 | KMO (0.50) | KMOCYP1A2RECQLDAOP2RX7 | |
| SCHEMBL9934410 | 0.84 | RECQL (0.61) | KMOCYP1A2RECQLDAOP2RX7 | |
| SCHEMBL29520779 | 0.84 | RECQL (0.61) | KMOCYP1A2RECQLDAOP2RX7 | |
| SCHEMBL14578727 | 0.84 | KMO (0.47) | KMOCYP1A2RECQLDAOP2RX7 | |
| SCHEMBL27997802 | 0.82 | RECQL (0.65) | KMOCYP1A2RECQLDAOP2RX7 | |
| SCHEMBL20083662 | 0.81 | CYP1A2 (0.62) | KMOCYP1A2RECQLDAOP2RX7 | |
| SCHEMBL5565705 | 0.81 | CYP1A2 (0.62) | KMOCYP1A2RECQLDAOP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250092014-A1 | COMPOUNDS AND METHODS OF ACTIVATING LIPOPROTEIN LIPASE | METREA BIOSCIENCES INC (US) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250092014-A1 | COMPOUNDS AND METHODS OF ACTIVATING LIPOPROTEIN LIPASE | LPL, LIPA, PNLIP | KMO 2002/4885CYP1A2 973/4885RECQL 1592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.