Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.41 |
| ▸ | TP53 | P04637 | 5/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20647783 | 0.86 | MAPT (0.39) | MAPTTP53LMNAALOX12THRB | |
| SCHEMBL20647781 | 0.82 | CYP3A4 (0.42) | MAPTTP53LMNAALOX12THRB | |
| SCHEMBL20647802 | 0.82 | MAPT (0.40) | MAPTTP53LMNATHRBSMN1; SMN2 | |
| SCHEMBL20647806 | 0.82 | MAPT (0.45) | MAPTTP53LMNATHRBSMN1; SMN2 | |
| SCHEMBL20647804 | 0.81 | MAPT (0.39) | MAPTTP53LMNATHRBSMN1; SMN2 | |
| SCHEMBL15076562 | 0.79 | MAPT (0.59) | MAPTTP53LMNASMN1; SMN2HTT | |
| SCHEMBL21844846 | 0.77 | MDM2 (0.42) | MAPTTRPV4LMNASMN1; SMN2PKM | |
| SCHEMBL20647758 | 0.77 | MAPT (0.39) | MAPTTP53THRBSMN1; SMN2HTT | |
| SCHEMBL15076826 | 0.77 | ENPP2 (0.53) | MAPTTP53LMNASMN1; SMN2HTT | |
| SCHEMBL19841963 | 0.76 | MAPT (0.48) | MAPTTP53LMNAALOX12SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-A1 | HEPATITIS B ANTIVIRAL AGENTS | Novira Therapeutics Inc. (US) | 2018-04-25 | — | — | EP | disclosed |