Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RBP4 | P02753 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30646383 | 1.00 | NPC1 (0.56) | NPC1POLBALDH1A1RBP4MAPT | |
| SCHEMBL1025669 | 0.85 | NPC1 (0.46) | NPC1POLBALDH1A1RBP4MAPT | |
| SCHEMBL27743576 | 0.85 | NPC1 (0.55) | NPC1POLBALDH1A1RBP4MAPT | |
| SCHEMBL29369561 | 0.83 | POLB (0.54) | NPC1POLBALDH1A1RBP4MAPT | |
| SCHEMBL379950 | 0.83 | POLB (0.54) | NPC1POLBALDH1A1RBP4MAPT | |
| SCHEMBL15514535 | 0.83 | NPC1 (0.54) | NPC1POLBALDH1A1RBP4MAPT | |
| SCHEMBL1966341 | 0.81 | SIRT3 (0.55) | NPC1POLBALDH1A1RBP4MAPT | |
| SCHEMBL13679245 | 0.81 | NPC1 (0.56) | NPC1POLBALDH1A1RBP4MAPT | |
| Hydrochloric Acid SCHEMBL3827644 | 0.81 | POLB (0.52) | NPC1POLBALDH1A1RBP4MAPT | |
| SCHEMBL679589 | 0.81 | NPC1 (0.52) | NPC1POLBALDH1A1RBP4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119638619-A | Indan pyridine amide compound and preparation method and application thereof | 盐城工学院 | 2025-03-18 | — | — | CN | claimed |
| CN-113929621-A | Synthesis method of flonicamid | 江西汇和化工有限公司 | 2022-01-14 | — | — | CN | claimed |
| CN-108892638-B | Preparation method of N-cyanomethyl-4- (trifluoromethyl) nicotinamide | 山东沾化永浩医药科技有限公司 | 2021-07-09 | — | — | CN | claimed |
| CN-107417606-B | Method for converting N-cyanomethyl bis (trifluoromethyl) nicotinamide into flonicamid and application | 河北科技大学 | 2020-07-10 | — | — | CN | claimed |
| CN-108892638-A | A kind of N- cyanogen methyl -4-（Trifluoromethyl）The preparation method of niacinamide | 山东沾化永浩医药科技有限公司 | 2018-11-27 | — | — | CN | claimed |
| CN-107417606-A | N cyanogen methyl is double（Trifluoromethyl）Niacinamide is converted into method and the application of flonicamid | 河北科技大学 | 2017-12-01 | — | — | CN | claimed |
| CN-107162966-A | The synthetic method of flonicamid | 无锡市稼宝药业有限公司 | 2017-09-15 | — | — | CN | claimed |
| JP-2007513075-A | — | — | 2007-05-24 | — | — | JP | claimed |
| CN-1882545-A | Substituted nicotinoylcarbamates as pesticides | BAYER CROPSCIENCE AG (DE) | 2006-12-20 | — | — | CN | claimed |
| EP-1685111-A1 | SUBSTITUTED NICOTINOYLCARBAMATES AS PESTICIDES | Bayer CropScience AG (DE) | 2006-08-02 | — | — | EP | claimed |
| WO-2005047255-A1 | SUBSTITUTED NICOTINOYLCARBAMATES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-05-26 | — | — | WO | claimed |
| CN-122010767-A | Haloalkyl bisamide compound and application thereof | 山东熙霖生物科技有限公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-120192278-A | Azole bisamide-containing compound and preparation method and application thereof | 江西天宇化工有限公司 | 2025-06-24 | — | — | CN | disclosed |
| CN-119954717-A | Flonicamid-contained insect-killing device Process for the preparation of amides | 安徽乐雍生物科技有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-116063285-B | Substituted pyrimidine (thio) ester compound and application thereof | 沈阳中化农药化工研发有限公司 | 2025-02-11 | — | — | CN | disclosed |
| EP-0580374-B1 | Pyridine amides and their salts, processes for their production and pesticidal compositions containing them | ISHIHARA SANGYO KAISHA (JP) | 1996-01-03 | — | — | EP | disclosed |
| US-5360806-A | Insecticides | ISHIHARA SANGYO KAISHA LTD. (JP) | 1994-11-01 | — | — | US | disclosed |
| CN-1081670-A | Amide compound and salt thereof, their manufacturing process and pesticide composition thereof | ISHIHARA SANGYO KAISHA (JP) | 1994-02-09 | — | — | CN | disclosed |
| EP-0580374-A1 | Pyridine amides and their salts, processes for their production and pesticidal compositions containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1994-01-26 | — | — | EP | disclosed |
| US-4788210-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |