Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RBP4 | P02753 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27743576 | 0.85 | NPC1 (0.55) | NPC1POLBMAPTRBP4ALDH1A1 | |
| SCHEMBL6626515 | 0.83 | TDP1 (0.43) | NPC1POLBMAPTALDH1A1SIRT3 | |
| SCHEMBL379950 | 0.83 | POLB (0.54) | NPC1POLBMAPTRBP4ALDH1A1 | |
| SCHEMBL29369561 | 0.83 | POLB (0.54) | NPC1POLBMAPTRBP4ALDH1A1 | |
| SCHEMBL15514535 | 0.83 | NPC1 (0.54) | NPC1POLBMAPTRBP4ALDH1A1 | |
| SCHEMBL8130335 | 0.82 | NPC1 (0.50) | NPC1POLBMAPTRBP4ALDH1A1 | |
| SCHEMBL3761522 | 0.82 | POLB (0.57) | NPC1POLBMAPTRBP4ALDH1A1 | |
| SCHEMBL13760452 | 0.82 | NPC1 (0.47) | NPC1POLBMAPTRBP4ALDH1A1 | |
| SCHEMBL2008577 | 0.81 | NPC1 (0.56) | NPC1POLBMAPTRBP4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3827644 | 0.81 | POLB (0.52) | NPC1POLBMAPTRBP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026086928-A1 | SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2026-04-30 | — | — | WO | disclosed |
| WO-2017108904-A1 | METHODS AND MEANS FOR THE ERADICATION OF FLEAS | CEVA SANTE ANIMALE (FR) | 2017-06-29 | — | — | WO | disclosed |
| US-20160287607-A1 | NON-RETINOID ANTAGONISTS FOR TREATMENT OF AGE-RELATED MACULAR DEGENERATION AND STARGARDT DISEASE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-10-06 | — | — | US | disclosed |
| US-9333202-B2 | Non-retinoid antagonists for treatment of age-related macular degeneration and stargardt disease | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-05-10 | — | — | US | disclosed |
| US-20150126494-A1 | NON-RETINOID ANTAGONISTS FOR TREATMENT OF AGE-RELATED MACULAR DEGENERATION AND STARGARDT DISEASE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2015-05-07 | — | — | US | disclosed |
| US-8841328-B2 | Selective insecticides based on anthranilic acid diamides and safeners | BAYER CROPSCIENCE AG (DE) | 2014-09-23 | — | — | US | disclosed |
| US-8841328-B2 | Selective insecticides based on anthranilic acid diamides and safeners | BAYER CROPSCIENCE AG (DE) | 2014-09-23 | — | — | US | disclosed |
| US-20140087946-A1 | Selective Insecticides Based on Anthranilic Acid Diamides and Safeners | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-03-27 | — | — | US | disclosed |
| US-20140087946-A1 | Selective Insecticides Based on Anthranilic Acid Diamides and Safeners | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-03-27 | — | — | US | disclosed |
| WO-2014023531-A1 | TRIFLUOROMETHYLPYRIDINE CARBOXAMIDES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-13 | — | — | WO | disclosed |
| US-20110059991-A1 | Selective Insecticides Based on Anthranilic Acid Diamides and Safeners | BAYER CROPSCIENCE AG (DE) | 2011-03-10 | — | — | US | disclosed |
| US-20110059991-A1 | Selective Insecticides Based on Anthranilic Acid Diamides and Safeners | BAYER CROPSCIENCE AG (DE) | 2011-03-10 | — | — | US | disclosed |
| US-20100160326-A1 | PEST CONTROL AGENT CONTAINING NOVEL PYRIDYL-METHANAMINE DERIVATIVE OR SALT THEREOF | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-06-24 | — | — | US | disclosed |
| US-20100160326-A1 | PEST CONTROL AGENT CONTAINING NOVEL PYRIDYL-METHANAMINE DERIVATIVE OR SALT THEREOF | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-06-24 | — | — | US | disclosed |
| US-7550458-B2 | Tricycloundecane compounds useful as modulators of nuclear hormone receptor function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-06-23 | — | — | US | disclosed |
| EP-2030971-A1 | PEST CONTROL AGENT CONTAINING NOVEL PYRIDYL-METHANAMINE DERIVATIVE OR SALT THEREOF | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2009-03-04 | — | — | EP | disclosed |
| US-20080221167-A1 | for controlling insects and/or arachnids | BAYER CROPSCIENCE AG (DE) | 2008-09-11 | — | — | US | disclosed |
| US-20080221167-A1 | for controlling insects and/or arachnids | BAYER CROPSCIENCE AG (DE) | 2008-09-11 | — | — | US | disclosed |
| US-7332509-B2 | Heterocyclic amides, a process for their preparation, compositions comprising them and their use | MERIAL LIMITED (US) | 2008-02-19 | — | — | US | disclosed |
| US-20070088029-A1 | Tricycloundecane compounds useful as modulators of nuclear hormone receptor function | BRISTOL-MYERS SQUIBB COMPANY | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160326-A1 | PEST CONTROL AGENT CONTAINING NOVEL PYRIDYL-METHANAMINE DERIVATIVE OR SALT THEREOF | HCN1, HCN3, HCN2 | NPC1 1513/4885POLB 4132/4885MAPT 4737/4885 |
| US-20150126494-A1 | NON-RETINOID ANTAGONISTS FOR TREATMENT OF AGE-RELATED MACULAR DEGENERATION AND STARGARDT DISEASE | RBP4, RBP1, LRAT | NPC1 116/4885POLB 2815/4885MAPT 1580/4885 |
| US-20160287607-A1 | NON-RETINOID ANTAGONISTS FOR TREATMENT OF AGE-RELATED MACULAR DEGENERATION AND STARGARDT DISEASE | RBP4, RBP1, LRAT | NPC1 116/4885POLB 2815/4885MAPT 1580/4885 |
| US-20140087946-A1 | Selective Insecticides Based on Anthranilic Acid Diamides and Safeners | DDC, DDT, AADAC | NPC1 3750/4885POLB 3372/4885MAPT 3813/4885 |
| US-20110059991-A1 | Selective Insecticides Based on Anthranilic Acid Diamides and Safeners | DDC, DDT, AADAC | NPC1 3750/4885POLB 3372/4885MAPT 3813/4885 |
| US-20070088029-A1 | Tricycloundecane compounds useful as modulators of nuclear hormone receptor function | VDR, ESRRB, NR5A1 | NPC1 618/4885POLB 2097/4885MAPT 4312/4885 |
| US-20080221167-A1 | for controlling insects and/or arachnids | CRYAB, DDC, DDT | NPC1 2987/4885POLB 3502/4885MAPT 3189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.