Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | WRN | Q14191 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20611006 | 0.79 | CYP3A4 (0.35) | ALDH1A1CYP1A2CYP2C19L3MBTL1MAPT | |
| SCHEMBL3684074 | 0.79 | CYP2C19 (0.41) | CYP2C19MT-CO2ALOX5L3MBTL1 | |
| SCHEMBL24311271 | 0.77 | MT-CO2 (0.50) | MT-CO2ALOX5 | |
| SCHEMBL25046381 | 0.75 | MT-CO2 (0.38) | MT-CO2ALOX5 | |
| SCHEMBL20646637 | 0.73 | TSHR (0.39) | ALDH1A1BLMHPGDGSK3AGSK3B | |
| SCHEMBL22561621 | 0.73 | ATM (0.34) | ALDH1A1CYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL3678842 | 0.73 | MAPT (0.33) | HPGDMAPT | |
| SCHEMBL9914761 | 0.71 | GSK3A (0.46) | ALDH1A1BLMCYP1A2HPGDCYP2C19 | |
| SCHEMBL14281129 | 0.71 | PTGS1 (0.38) | ALDH1A1BLMCYP1A2HPGDCYP2C19 | |
| SCHEMBL4326673 | 0.70 | POLB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11001593-B2 | Rigid dinitroxide biradical compounds used as improved polarizing agents for dynamic nuclear polarization techniques | UNIVERSITE D'AIX-MARSEILLE (FR) | 2021-05-11 | — | — | US | disclosed |
| US-10398783-B2 | Antiproliferative compounds and conjugates made therefrom | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-09-03 | — | — | US | disclosed |
| US-20180110873-A1 | ANTIPROLIFERATIVE COMPOUNDS AND CONJUGATES MADE THEREFROM | BRISTOL-MYERS SQUIBB COMPANY | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180110873-A1 | ANTIPROLIFERATIVE COMPOUNDS AND CONJUGATES MADE THEREFROM | MKI67, HDGF, PCLAF | ALDH1A1 314/4885BLM 4570/4885CYP1A2 2740/4885 |
| US-11001593-B2 | Rigid dinitroxide biradical compounds used as improved polarizing agents for dynamic nuclear polarization techniques | CCNO, CCNA1, CCND1 | ALDH1A1 3677/4885BLM 3628/4885CYP1A2 3261/4885 |
| US-10398783-B2 | Antiproliferative compounds and conjugates made therefrom | MKI67, HDGF, PCLAF | ALDH1A1 314/4885BLM 4570/4885CYP1A2 2740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.