Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.51 |
| ▸ | RCOR1 | Q9UKL0 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21451882 | 0.91 | PTPN1 (0.46) | KDM1ARCOR1RAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL20527158 | 0.89 | PTPN1 (0.44) | KDM1ARCOR1RAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28250003 | 0.85 | MEN1 (0.48) | RAB9AMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL20485567 | 0.83 | HRAS (0.45) | KDM1ARCOR1MAPTLMNATP53 | |
| SCHEMBL5467775 | 0.83 | HRAS (0.45) | KDM1ARCOR1MAPTLMNATP53 | |
| SCHEMBL20515027 | 0.83 | NR1H4 (0.53) | KDM1ARCOR1ALDH1A1HDAC1 | |
| SCHEMBL16693559 | 0.83 | RAB9A (0.54) | KDM1ARCOR1RAB9AMEN1KMT2A | |
| SCHEMBL20527335 | 0.81 | LMNA (0.44) | RAB9AMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL16691871 | 0.81 | KDM1A (0.51) | KDM1ARCOR1RAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL20527208 | 0.80 | RXFP1 (0.54) | RAB9AMEN1KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602803-A | Piperidinobenzodiazepine compounds with antiproliferative activity | 福姆通格尼克斯有限公司 | 2018-09-28 | — | — | CN | disclosed |
| US-20180110873-A1 | ANTIPROLIFERATIVE COMPOUNDS AND CONJUGATES MADE THEREFROM | BRISTOL-MYERS SQUIBB COMPANY | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180110873-A1 | ANTIPROLIFERATIVE COMPOUNDS AND CONJUGATES MADE THEREFROM | MKI67, HDGF, PCLAF | KDM1A 2346/4885RCOR1 4207/4885RAB9A 3108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.