Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.53 |
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.34 |
| ▸ | PER2 | O15055 | 2/20 | 0.33 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.33 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.32 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.32 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20087387 | 0.86 | CA12 (0.53) | CA12CA1CA14CA7CA2 | |
| SCHEMBL20136933 | 0.85 | CA12 (0.37) | CA12CA1CA14CA7CA2 | |
| SCHEMBL22345342 | 0.82 | CA12 (0.36) | CA12CA1CA14CA7NR1D1 | |
| SCHEMBL16558052 | 0.76 | MAPK1 (0.51) | CA12CA1CA14CA7CA2 | |
| SCHEMBL6700697 | 0.76 | CA12 (0.43) | CA12CA1CA14CA7CA2 | |
| SCHEMBL20087394 | 0.75 | AKT1 (0.36) | CA12CA1CA14CA7NR1D1 | |
| SCHEMBL16558057 | 0.75 | NR1D1 (0.58) | CA12CA1CA14CA7CA2 | |
| SCHEMBL16558055 | 0.74 | RORC (0.47) | CA12CA1CA14CA7CA9 | |
| SCHEMBL13145857 | 0.74 | CA12 (0.42) | CA12CA1CA14CA7CA2 | |
| SCHEMBL19199788 | 0.74 | MEN1 (0.36) | CA12CA1CA14CA7CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180133340-A1 | ANTIBODY-DRUG CONJUGATES | CHO Pharma Inc. (TW) | 2018-05-17 | — | — | US | disclosed |
| US-20180110876-A1 | NOVEL HYDROPHILIC LINKERS AND LIGAND-DRUG CONJUGATES THEREOF | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180133340-A1 | ANTIBODY-DRUG CONJUGATES | CSGALNACT1, ST6GAL1, PA2G4 | CA12 97/4885CA1 469/4885CA14 216/4885 |
| US-20180110876-A1 | NOVEL HYDROPHILIC LINKERS AND LIGAND-DRUG CONJUGATES THEREOF | CD44, HACD3, HACD2 | CA12 905/4885CA1 1649/4885CA14 745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.