Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | NAE1 | Q13564 | 2/20 | 0.30 |
| ▸ | UBA1 | P22314 | 1/20 | 0.30 |
| ▸ | UBA3 | Q8TBC4 | 1/20 | 0.30 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.30 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17523546 | 0.93 | CA2 (0.34) | CA2 | |
| SCHEMBL14806825 | 0.93 | CA2 (0.34) | CA2 | |
| SCHEMBL14820596 | 0.93 | CA2 (0.34) | CA2 | |
| SCHEMBL21022513 | 0.92 | CA2 (0.33) | CA2 | |
| SCHEMBL24518381 | 0.91 | CA2 (0.34) | CA2 | |
| SCHEMBL25541258 | 0.89 | CA2 (0.33) | CA2 | |
| SCHEMBL17227477 | 0.89 | CA2 (0.33) | CA2 | |
| SCHEMBL21123041 | 0.88 | CA2 (0.35) | CA2 | |
| SCHEMBL18412182 | 0.87 | CA2 (0.34) | CA2 | |
| SCHEMBL17636632 | 0.87 | CA2 (0.32) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10239909-B2 | Polymethine compounds with long stokes shifts and their use as fluorescent labels | ILLUMINA CAMBRIDGE LIMITED (GB) | 2019-03-26 | — | — | US | disclosed |
| US-20180111957-A1 | POLYMETHINE COMPOUNDS WITH LONG STOKES SHIFTS AND THEIR USE AS FLUORESCENT LABELS | ILLUMINA CAMBRIDGE LTD. (GB) | 2018-04-26 | — | — | US | disclosed |
| US-20180111957-A1 | POLYMETHINE COMPOUNDS WITH LONG STOKES SHIFTS AND THEIR USE AS FLUORESCENT LABELS | ILLUMINA CAMBRIDGE LTD. (GB) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180111957-A1 | POLYMETHINE COMPOUNDS WITH LONG STOKES SHIFTS AND THEIR USE AS FLUORESCENT LABELS | POLRMT, FBL, NOP2 | CA2 3778/4885NAE1 2286/4885UBA1 3808/4885 |
| US-10239909-B2 | Polymethine compounds with long stokes shifts and their use as fluorescent labels | POLRMT, FBL, NOP2 | CA2 3778/4885NAE1 2286/4885UBA1 3808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.