Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Taiwaniaquinol D SCHEMBL18105235 | 0.84 | AKR1B1 (0.35) | — | |
| Taiwaniaquinol D SCHEMBL31237203 | 0.84 | AKR1B1 (0.35) | — | |
| SCHEMBL4778751 | 0.70 | CACNA1G (0.31) | — | |
| Taiwaniaquinone D SCHEMBL31237587 | 0.64 | — | — | |
| SCHEMBL20089279 | 0.63 | USP2 (0.39) | — | |
| SCHEMBL4967470 | 0.55 | BCL2 (0.34) | BCL2MCL1 | |
| SCHEMBL19020514 | 0.54 | LDHA (0.36) | BCL2MCL1 | |
| SCHEMBL11653101 | 0.54 | BCL2 (0.38) | BCL2MCL1 | |
| SCHEMBL31571680 | 0.52 | CACNA1G (0.31) | — | |
| SCHEMBL10888504 | 0.52 | MAOB (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180111889-A1 | METHODS OF MAKING MULTICYCLIC COMPOUNDS USING MULTICOMPONENT/TANDEM REACTION SEQUENCES | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, (US) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180111889-A1 | METHODS OF MAKING MULTICYCLIC COMPOUNDS USING MULTICOMPONENT/TANDEM REACTION SEQUENCES | TYMS, RTCB, POLRMT | BCL2 1774/4885MCL1 187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.