Sugi Predict

Sugi Predict / Compounds / SCHEMBL9657338

SCHEMBL9657338

SCHEMBL9657338

CCOCCOCC(COCCOCC)OCCOCC

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ LPAR1 Q92633 4/20 0.39
▸ LPAR3 Q9UBY5 4/20 0.39
▸ LPAR2 Q9HBW0 1/20 0.39
▸ ALDH1A1 P00352 2/20 0.38
▸ TSHR P16473 1/20 0.36
▸ DNM1 Q05193 1/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ THRB P10828 2/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ USP2 O75604 1/20 0.30
▸ TLR2 O60603 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18281575 0.89 LPAR1 (0.38) LPAR1LPAR3LPAR2ALDH1A1TSHR
SCHEMBL20089588 0.89 HSD17B10 (0.40) LPAR1LPAR3LPAR2ALDH1A1TSHR
SCHEMBL17642219 0.88 ALDH1A1 (0.33) LPAR1LPAR3LPAR2ALDH1A1TSHR
SCHEMBL17642247 0.88 ALDH1A1 (0.33) LPAR1LPAR3LPAR2ALDH1A1TSHR
SCHEMBL23768408 0.87 ALDH1A1 (0.56) LPAR1LPAR3LPAR2ALDH1A1TSHR
SCHEMBL19543564 0.87 ALDH1A1 (0.56) LPAR1LPAR3LPAR2ALDH1A1TSHR
SCHEMBL17676296 0.83 LPAR1 (0.37) LPAR1LPAR3LPAR2TLR2
SCHEMBL19543622 0.82 LPAR1 (0.38) LPAR1LPAR3LPAR2DNM1HSD17B10
SCHEMBL23408864 0.82 HSD17B10 (0.46) LPAR1LPAR3LPAR2TSHRDNM1
SCHEMBL20438744 0.81 ALDH1A1 (0.32) LPAR1LPAR3LPAR2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220165361-A1 METHODS OF DIAGNOSING DISEASE 4D Pharma Cork Limited (IE) 2022-05-26 — — US claimed
EP-3947744-A1 METHODS OF DIAGNOSING DISEASE 4D Pharma Cork Limited (IE) 2022-02-09 — — EP claimed
WO-2020201458-A1 METHODS OF DIAGNOSING DISEASE 4D Pharma Cork Limited (IE) 2020-10-08 — — WO claimed
US-5079023-A During consumption; beverages HERCULES INCORPORATED (US) 1992-01-07 — — US claimed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 — — US disclosed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 — — US disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 — — EP disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 — — US disclosed
EP-3947743-A1 METHODS OF DIAGNOSING DISEASE 4D Pharma Cork Limited (IE) 2022-02-09 — — EP disclosed
EP-3947744-A1 METHODS OF DIAGNOSING DISEASE 4D Pharma Cork Limited (IE) 2022-02-09 — — EP disclosed
US-20210227863-A1 HIGH INTENSITY SWEETENERS SENOMYX, INC. 2021-07-29 — — US disclosed
EP-3356356-B1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED (US) 2021-05-26 — — EP disclosed
US-20170143022-A1 Compositions Incorporating an Umami Flavor Agent SENOMYX INC (US) 2017-05-25 — — US disclosed
WO-2017075257-A2 HIGH INTENSITY SWEETENERS SENOMYX, INC. (US) 2017-05-04 — — WO disclosed
US-20170119032-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED 2017-05-04 — — US disclosed
US-20170096418-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED 2017-04-06 — — US disclosed
US-20170087199-A1 COMPOSITIONS FOR DELIVERING A COOLING SENSATION SENOMYX INC (US) 2017-03-30 — — US disclosed
US-20160376263-A1 BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF SENOMYX INC (US) 2016-12-29 — — US disclosed
US-5079023-A During consumption; beverages HERCULES INCORPORATED (US) 1992-01-07 — — US disclosed
US-4280011-A FLAVORINGS HERCULES INCORPORATED (US) 1981-07-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 LPAR1 3679/4885LPAR3 3752/4885LPAR2 3941/4885
US-20170119032-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 LPAR1 3679/4885LPAR3 3752/4885LPAR2 3941/4885
US-20160376263-A1 BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF TAS2R5, TAS1R1, TAS2R1 LPAR1 1905/4885LPAR3 1433/4885LPAR2 2420/4885
US-11357246-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 LPAR1 3679/4885LPAR3 3752/4885LPAR2 3941/4885
US-20170143022-A1 Compositions Incorporating an Umami Flavor Agent TAS2R8, TAS2R45, TAS2R40 LPAR1 3389/4885LPAR3 3749/4885LPAR2 3679/4885
US-20170087199-A1 COMPOSITIONS FOR DELIVERING A COOLING SENSATION TRPA1, PDE6G, PDE6D LPAR1 2363/4885LPAR3 2506/4885LPAR2 3148/4885
US-20210227863-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 LPAR1 3679/4885LPAR3 3752/4885LPAR2 3941/4885
US-11758933-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 LPAR1 3679/4885LPAR3 3752/4885LPAR2 3941/4885
US-20170096418-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 TRPM8, TRPM6, TRPM4 LPAR1 1286/4885LPAR3 1097/4885LPAR2 816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.