Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRF1 | P14222 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | CHUK | O15111 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27999718 | 0.92 | PTGS1 (0.33) | PRF1ACHEPDCD1CD274ESR1 | |
| SCHEMBL20095842 | 0.92 | WRN (0.32) | PRF1ACHEPDCD1CD274ESR1 | |
| SCHEMBL20089639 | 0.86 | — | — | |
| SCHEMBL3472776 | 0.84 | ESR2 (0.46) | ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL5466664 | 0.84 | ESR1 (0.36) | ESR1ESR2HSD17B1HSD17B2PLA2G10 | |
| SCHEMBL20527880 | 0.81 | APP (0.39) | PRF1HSD17B10PLA2G10KDM4ENPC1 | |
| SCHEMBL423920 | 0.81 | PLA2G10 (0.41) | ESR1ESR2HSD17B1HSD17B2HSD17B10 | |
| SCHEMBL13164291 | 0.80 | ESR1 (0.42) | ESR1ESR2HSD17B1HSD17B2PLA2G10 | |
| SCHEMBL28337823 | 0.80 | HDAC1 (0.42) | IKBKBPLA2G10SMN1; SMN2 | |
| SCHEMBL8368346 | 0.80 | HDAC6 (0.44) | PRF1HSD17B1PTGS1KIF11PLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11143332-B2 | Hose with tunable flexibility using cyclizable, photochromic molecules | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2021-10-12 | — | — | US | disclosed |
| US-10927976-B2 | Hose with tunable flexibility using cyclizable, photochromic molecules | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2021-02-23 | — | — | US | disclosed |
| US-20190285195-A1 | HOSE WITH TUNABLE FLEXIBILITY USING CYCLIZABLE, PHOTOCHROMIC MOLECULES | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2019-09-19 | — | — | US | disclosed |
| US-20180112018-A1 | HOSE WITH TUNABLE FLEXIBILITY USING CYCLIZABLE, PHOTOCHROMIC MOLECULES | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2018-04-26 | — | — | US | disclosed |