SCHEMBL2008995

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2008997	1.00	LMNA (0.49)	LMNAALDH1A1MEN1KMT2ALTA4H
	SCHEMBL2009647	0.89	LMNA (0.51)	LMNAALDH1A1MEN1KMT2ALTA4H
	SCHEMBL2007627	0.89	LMNA (0.49)	LMNAALDH1A1MEN1KMT2ALTA4H
	SCHEMBL2007624	0.89	LMNA (0.49)	LMNAALDH1A1MEN1KMT2ALTA4H
	SCHEMBL2009645	0.89	LMNA (0.51)	LMNAALDH1A1MEN1KMT2ALTA4H
	SCHEMBL4686173	0.85	LMNA (0.47)	LMNAALDH1A1MEN1KMT2ALTA4H
	SCHEMBL4686176	0.85	LMNA (0.47)	LMNAALDH1A1MEN1KMT2ALTA4H
	SCHEMBL2010181	0.84	CNR1 (0.45)	LMNAALDH1A1MEN1KMT2ATSHR
	SCHEMBL12569198	0.81	TSHR (0.50)	LMNAALDH1A1MEN1KMT2ATSHR
	SCHEMBL2005349	0.77	CNR1 (0.40)	LMNAALDH1A1MEN1KMT2ACNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.