Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.46 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1285506 | 0.94 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL20090041 | 0.93 | ZDHHC20 (0.48) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL27428987 | 0.86 | ZDHHC20 (0.47) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL13763001 | 0.84 | ZDHHC20 (0.35) | ZDHHC20ZDHHC2GAA | |
| SCHEMBL16788734 | 0.84 | ZDHHC20 (0.46) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL14844645 | 0.81 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL307977 | 0.81 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL515065 | 0.80 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL675801 | 0.79 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL20090043 | 0.79 | ZDHHC20 (0.30) | ZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180113237-A1 | AMPHIPHILIC BRANCHED POLYDIORGANOSILOXANE MACROMERS | ALCON INC. (CH) | 2018-04-26 | — | — | US | disclosed |