SCHEMBL307977

SCHEMBL307977

C=CC(=O)NCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.51
ZDHHC2 Q9UIJ5 1/20 0.51
TSHR P16473 3/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TGM2 P21980 9/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.32
KMT5A Q9NQR1 1/20 0.32
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31
HPGD P15428 1/20 0.31
MTNR1A P48039 1/20 0.30
MTNR1B P49286 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL515065 0.98 ZDHHC20 (0.50) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL9396182 0.92 ZDHHC20 (0.45) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL9396060 0.92 ZDHHC20 (0.45) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL9396161 0.87 ZDHHC20 (0.49) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL27994509 0.87 ZDHHC20 (0.43) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL1285506 0.86 ZDHHC20 (0.51) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL14844645 0.86 ZDHHC20 (0.51) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL851909 0.85 ZDHHC20 (0.51) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL30998151 0.84 ZDHHC20 (0.36) ZDHHC20ZDHHC2ALDH1A1KMT2A
SCHEMBL851109 0.84 ZDHHC20 (0.54) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 954 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2187243-B2 Colored ink for pad transfer printing of silicone hydrogel lenses ALCON INC (CH) 2025-07-09 EP claimed
CN-119799112-A Novel marine antifouling hydrogel coating material and preparation method and application thereof 南京大学 2025-04-11 CN claimed
CN-119638918-A Colored silicon polymer material and preparation method thereof 江苏天眼医药科技股份有限公司 2025-03-18 CN claimed
CN-119569962-A Silicon polymer material and preparation method thereof 烟台爱博诺德医用材料有限公司 2025-03-07 CN claimed
CN-116715800-B Blue light resistant contact lens and preparation method thereof 江苏海伦隐形眼镜有限公司 2025-01-10 CN claimed
CN-118930724-A Hydrogel lens and preparation method thereof 海昌隐形眼镜有限公司 2024-11-12 CN claimed
CN-118878758-A Contact lens material and preparation method thereof 海昌隐形眼镜有限公司 2024-11-01 CN claimed
CN-116836145-B Polymerizable photochromic compound and application thereof 重庆蕾明视光科技有限公司 2024-06-14 CN claimed
US-20240159938-A1 Compositions for Ophthalmologic Devices JOHNSON & JOHNSON VISION CARE, INC. 2024-05-16 US claimed
CN-117720694-A Multi-monomer silicon material mixed copolymerization silicon hydrogel material, preparation method and application thereof, and preparation method of cornea contact lens 海昌隐形眼镜有限公司 2024-03-19 CN claimed
WO-2006002897-A1 SILICONE HYDROGELS WITH LATHABILITY AT ROOM TEMPERATURE NOVARTIS AG (CH) 2006-01-12 WO claimed
US-20060004165-A1 Silicone hydrogels with lathability at room temperature NOVARTIS AG (CH) 2006-01-05 US claimed
WO-2005102675-A2 CURABLE COLORED INKS FOR MAKING COLORED SILICONE HYDROGEL LENSES NOVARTIS AG (CH) 2005-11-03 WO claimed
US-20050237483-A1 Curable colored inks for making colored silicone hydrogel lenses ALCON INC. (CH) 2005-10-27 US claimed
WO-2005098478-A1 COLORED INK FOR PAD TRANSFER PRINTING OF SILICONE HYDROGEL LENSES NOVARTIS AG (CH) 2005-10-20 WO claimed
US-20050218536-A1 Colored ink for pad transfer printing of silicone hydrogel lenses ALCON INC. (CH) 2005-10-06 US claimed
EP-0675910-B1 NOVEL MACROMONOMERS BAUSCH & LOMB (US) 1997-09-17 EP claimed
EP-0675910-A1 NOVEL MACROMONOMERS. BAUSCH & LOMB (US) 1995-10-11 EP claimed
US-5336797-A Polymerizable with acrylic monomers and acrylated polyethers; contact lenses BAUSCH & LOMB INCORPORATED (US) 1994-08-09 US claimed
WO-1994015980-A1 NOVEL MACROMONOMERS BAUSCH & LOMB INCORPORATED (US) 1994-07-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240159938-A1 Compositions for Ophthalmologic Devices PDE6D, CRYAB, PDE6H ZDHHC20 1573/4885ZDHHC2 3228/4885TSHR 3951/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.