SCHEMBL675801

SCHEMBL675801

C=CC(=O)NCCC[Si](C)(OC)OC

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.53
ZDHHC2 Q9UIJ5 1/20 0.53
TSHR P16473 2/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
TGM2 P21980 9/20 0.39
GAA P10253 1/20 0.39
KMT5A Q9NQR1 1/20 0.35
MAPT P10636 1/20 0.33
MTNR1A P48039 3/20 0.33
MTNR1B P49286 3/20 0.33
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
EPHX1 P07099 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9067237 0.86 ZDHHC20 (0.53) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL1285506 0.84 ZDHHC20 (0.51) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL27658134 0.84 MAPT (0.34) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL761985 0.84 ZDHHC20 (0.55) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL114687 0.83 ZDHHC20 (0.54) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL17088131 0.82 ZDHHC20 (0.53) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL1147756 0.81 ZDHHC20 (0.60) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL1083676 0.81 SMN1; SMN2 (0.41) ZDHHC20ZDHHC2ALDH1A1MTNR1AMTNR1B
SCHEMBL4349259 0.80 ZDHHC20 (0.55) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL6276039 0.79 ZDHHC20 (0.58) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2158283-B1 MOISTURE-CURABLE, GRAFT-MODIFIED RESIN COMPOSITION, PROCESS FOR ITS MANUFACTURE AND PROCESS FOR BONDING SUBSTRATES EMPLOYING THE RESIN COMPOSITION MOMENTIVE PERFORMANCE MAT INC (US) 2017-10-18 EP claimed
US-8063140-B2 Moisture-curable, graft-modified resin composition, process for its manufacture and process for bonding substrates employing the resin composition MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-11-22 US claimed
EP-2158283-A1 MOISTURE-CURABLE, GRAFT-MODIFIED RESIN COMPOSITION, PROCESS FOR ITS MANUFACTURE AND PROCESS FOR BONDING SUBSTRATES EMPLOYING THE RESIN COMPOSITION Momentive Performance Materials Inc. (US) 2010-03-03 EP claimed
WO-2008156611-A1 MOISTURE-CURABLE, GRAFT-MODIFIED RESIN COMPOSITION, PROCESS FOR ITS MANUFACTURE AND PROCESS FOR BONDING SUBSTRATES EMPLOYING THE RESIN COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-12-24 WO claimed
US-20080311419-A1 Moisture-curable, graft-modified resin composition, process for its manufacture and process for bonding substrates employing the resin composition MOMENTIVE PERFORMANCE MATERIALS INC. 2008-12-18 US claimed
US-20250223225-A1 CONSTRUCTION MATERIAL DRY MIXES CONTAINING SOLID VINYL ESTER RESINS WACKER CHEMIE AG (DE) 2025-07-10 US disclosed
WO-2025023143-A1 GLASS CLOTH TREATMENT LIQUID AND SURFACE TREATED GLASS CLOTH 信越化学工業株式会社 2025-01-30 WO disclosed
CN-117794879-A Dry mixtures of building materials comprising solid vinyl ester resins 瓦克化学股份公司 2024-03-29 CN disclosed
CN-111836841-B Water-soluble copolymer 瓦克化学股份公司 2022-07-29 CN disclosed
EP-3556731-A1 METHOD FOR THE CHEMICAL MODIFICATION OF METAL OXIDE SURFACES Justus-Liebig-Universität Gießen (DE) 2019-10-23 EP disclosed
EP-2158283-B1 MOISTURE-CURABLE, GRAFT-MODIFIED RESIN COMPOSITION, PROCESS FOR ITS MANUFACTURE AND PROCESS FOR BONDING SUBSTRATES EMPLOYING THE RESIN COMPOSITION MOMENTIVE PERFORMANCE MAT INC (US) 2017-10-18 EP disclosed
US-8367748-B2 Surface-modified fillers IVOCLAR VIVADENT AG (LI) 2013-02-05 US disclosed
US-20080311419-A1 Moisture-curable, graft-modified resin composition, process for its manufacture and process for bonding substrates employing the resin composition MOMENTIVE PERFORMANCE MATERIALS INC. 2008-12-18 US disclosed
US-20080285133-A1 Antireflection Film, Production Method Thereof, Polarizing Plate Using the Antireflection Film and Image Display Device Using the Antireflection Film or Polarizing Plate FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20070086091-A1 Antireflection film, polarizing plate, and image display device including the same FUJIFILM CORPORATION (JP) 2007-04-19 US disclosed
EP-1716836-A1 Surface-modified fillers Ivoclar Vivadent AG (LI) 2006-11-02 EP disclosed
US-20060247329-A1 Surface-modified fillers IVOCLAR VIVADENT AG (LI) 2006-11-02 US disclosed
EP-0691363-B1 Polystyrene modified with a telechelic polyorganosiloxane DOW CORNING (US) 1997-09-03 EP disclosed
US-5502107-A IMPACT STRENGTH DOW CORNING CORPORATION (US) 1996-03-26 US disclosed
EP-0691363-A1 Polystyrene modified with a telechelic polyorganosiloxane DOW CORNING CORPORATION (US) 1996-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060247329-A1 Surface-modified fillers MSR1, HRH4, OR10J3 ZDHHC20 1730/4885ZDHHC2 3218/4885TSHR 1605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.